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Mind the gap – developing a sustainable pipeline for hearing therapeutics
In this article, the authors describe three key challenges faced in developing hearing therapeutics. Collaboration between companies, sectors and disciplines will be key to finding solutions. The unmet need for therapies for hearing loss grows apace, with prevalence rising across...
When should revision FESS leave you reaching for the script pad?
This very interesting work from the professorial team in London seeks to define a group of patients with CRSwNP who may benefit from early biological treatment since they are at risk of failure of surgical and conventional medical management. Approximately...Promoting human rights of deaf communities in low-resource settings
Stigma and misconceptions about deafness are serious impediments for many deaf people to realise rights and potential in some of the most challenging situations globally. Around 430 million people are estimated to live with moderate or higher levels of hearing...Promoting human rights of deaf communities in low-resource settings
Stigma and misconceptions about deafness are serious impediments for many deaf people to realise rights and potential in some of the most challenging situations globally. Around 430 million people are estimated to live with moderate or higher levels of hearing...
OTO-104 in noise-induced and cisplatin-induced hearing loss
These two animal studies report on potential new applications for intra-tympanic OTO-104, a slow-release hydrogel formulation of dexamethasone that is currently being used in a Europe-wide randomised trial for Ménière’s disease. In the first paper, guinea pigs were given a...
Olfactory ensheathing cells and their safe harvest
This interesting and unique paper not only demonstrates that biopsy of olfactory mucosa in the region of the superior turbinate is a safe procedure but also provides valuable insight into an engaging area of research by a world class team...AOT Conference 2024
Shared Knowledge, Built Community Anita Sedghi FY1, Northwick Park Hospital, London Northwest NHS Trust The AOT Conference this year focused on a diverse range of presentations, catering to trainees at all levels. The program started with a thought-provoking talk by...The UK National Eye Health and Hearing Study
A pilot study is currently underway in preparation for a UK National Eye Health and Hearing Study (UKNEHS). This will help to ensure an up-to-date and comprehensive picture of sight and hearing loss among over 50s in the UK.
Canopy: a medical translation app
Professional interpreters perform an integral role in the medical setting, ensuring that clinician-patient interactions are understood from both sides. As essential as they are, however, we have all experienced scenarios where we have been left, to our own devices, so...
A multidisciplinary approach to the management of frontal sinus fracture
Frontal sinus fractures account for about 5% of all facial trauma. Fractures of the posterior wall may result in cerebrospinal fluid (CSF) leak and meningitis, while obstruction of the outflow tract can cause sinusitis and mucocele formation. However, there are...
Use of topical steroids and antibiotics, compared to systemic antibiotics in the treatment of acute rhinusinusitis
Acute rhinusinusitis is mainly initiated by viral infections. Bacterial infection is usually superadded. The inflammatory cascade upregulates the pro-inflammatory mediators resulting in pain, nasal obstruction and nasal discharge. Local application of steroids and antibiotics could provide a higher concentration of...
