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IL-25 and nasal polyps, another target

Immune response in chronic rhinosinusitis with nasal polyps (CRSwNP) is mainly via type 2 T-helper (Th2) cells while Th1 cells characterise chronic rhinosinusitis without nasal polyps (CRSsNP) immune response. CRSwNP is heterogeneous on a cytological level causing a varied response...

Aerosols and polypi

Infection in the operative cavities after endoscopic sinus surgery for sinonasal polyposis leads to recurrence of symptoms and mucopurulent discharge. The usual therapies include systemic antibiotics sometimes with steroids. The authors hypothesised that the use of a topical antimicrobial (tobramycin...

N-acetylcysteine may have a role in the protection of cochlear hair cells

Gentamycin is an aminoglycoside antibiotic which is widely used throughout the world, despite its ototoxic potential. It therefore seems wise to continue the search for accessible otoprotective agents. The aim of this study was to clarify the potential protective role...

Postinfectious olfactory disorders

Recovery of olfactory function following URTI is frequent, even many years after the infectious insult. Upper respiratory tract infection is the commonest cause of olfactory loss. Many treatment options exist including topical steroids, vitamin B, acupuncture, and zinc, which can...

Is there evidence to support early discharge of patients with tonsillitis, quinsy and epistaxis?

The COVID-19 pandemic, with its unprecedented pressures on the NHS, demands changes in the management of common ENT emergencies. In this review article, information has been gleaned from 22 relevant articles on how this can be done. The Portsmouth tonsillitis...

True Cut – a dramatic biopsy from the world of surgery

True Cut is a stage play that asks: “What happens when things go wrong in healthcare?” It brings the hidden world of the operating theatre onto the theatre stage. ENT surgeon, David Alderson, talks about how the play came about....

TWJ Fellowship – Toronto 2015: Endoscopic Ear Surgery

The Thomas Wickham Jones (TWJ) Foundation is a charitable trust with the aim of helping patients with deafness overcome their disability. Striving to achieve this goal they provide educational grants to otolaryngologists and other related audiological professionals working within the...

The otolaryngologist as hospital director: a view from Thailand

Nadtaya Mills is a female otolaryngologist and director of an entire hospital in Thailand. In this article, she offers a fascinating insight to the work she’s done so far to improve resources and services in a challenging environment. The main...

The role of training programmes in protecting patients

ENT trainees are fully registered doctors who have responsibilities to comply with the requirements of Good Medical Practice. This includes ensuring that they put the interests of their patients at the heart of their practice. This duty is complementary to...

Clinical leadership and management: developing world ENT

I have been asked to share some of the initiatives I have been involved with to address ENT-related challenges in Africa and the developing world. Developing countries constitute the majority of the world’s landmass (Figure 1), are home to >50%...

In conversation with Professor Seiji Kakehata

Endoscopic ear surgery has been a rapidly evolving area of clinical practice in recent years. Our Global Ambassador in the Far East/ASEAN Region, Professor Tatsuya Yamasoba talks to one of the main exponents of this technique, and about the next...

The impact of dyslexia and neurodiversity on training and work – real-world consultant experiences

Awareness of dyslexia and its challenges in ENT training may enhance support for future trainees and trainers alike. Receiving a diagnosis of dyslexia or neurodivergence can be daunting, especially for a resident doctor with aspirations to pursue an ENT career....