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Expanding the role of FNA in thyroid nodule decision-making

Papillary thyroid cancer, the commonest histological type, has been extensively reported as having BRAF proto-oncogene mutations (most commonly the V600E mutation). There is great interest in BRAF as a molecular marker, particularly as a prognostic factor that may guide the...

Food impaction in children is associated with eosinophilic oesophagitis

There is an increasing amount of evidence to suggest that chronic oesophageal inflammation and motility disorders play a more significant role in oesophageal food impaction (EFI) in children compared to structural defects. The authors conducted a retrospective study of children...

Elevated prevalence of late-onset dysphagia among head and neck cancer survivors and identifying risk factors

Dysphagia is one of the most common problems affecting head and neck cancer (HNC) survivors. There are few studies investigating late-onset dysphagia post-treatment. The authors set out to investigate the prevalence of dysphagia-related diagnoses and procedures five years’ post-treatment, changes...

The polyp shrinker

Inflammatory markers, including T2 cells beta common (βc) cytokines IL-3, IL5 and granulocyte-macrophage colony-stimulating factor (GM-CSF), are known to play an important role in chronic rhinosinusitis with nasal polyps (CRSwNP). CSL311, a monoclonal antibody (mAb), was developed to target human...

Postoperative ultrasound surveillance in patients undergoing hemithyroidectomy

Hemithyroidectomy, as opposed to total thyroidectomy with radioiodine remnant ablation, is now increasingly undertaken for low-risk, differentiated thyroid cancer. If on histology, this proves ‘high risk’, completion thyroidectomy is done fairly soon. In this retrospective study, a total of 105...

Clinical Head and Neck Anatomy for Surgeons

The head and neck anatomy is a complex area and if one simply wanted to just learn and revise anatomy, it would be reasonable to pick up an anatomy book for reference. However, it can be helpful to have a...

Cholesteatoma and Ear Surgery

The book Cholesteatoma and Ear Surgery is a selection of papers and presentations, including round tables and symposia, that constitute the proceedings of the 10th International Conference on Cholesteatoma and Ear surgery, a highly successful meeting that attracted over 1000...

Helicobacter pylori and chronic tonsillitis

Helicobacter pylori infection in the stomach has long been associated with chronic gastritis, duodenal and peptic ulceration and even gastric cancer. Whether laryngopharyngeal reflux (LPR) brings up these organisms and induces chronic tonsillitis is an interesting concept, which the authors...

Application of balloon dilatation in chronic eustachian tube dysfunction

Chronic eustachian tube dysfunction prevails in 1% of the adult population and can predispose to middle ear disease. There are subjective and objective features of this condition that can affect quality of life. The common methods to treat eustachian tube...

Diagnosis of obstructive sleep apnoea hypopneoa syndrome (OSAHS) without sleep studies

Polysomnography is considered the ‘gold standard’ in the diagnosis of sleep apnoea but it is expensive and difficult to perform in children. Diagnosis based on subjective judgement is often inaccurate. An accurate diagnostic scale based on clinical parameters could obviate...

Effects of age on neuro-physiological processing of speech at brainstem level

Degenerative changes associated with ageing may affect processing of spectral and temporal cues in speech at cortical and subcortical levels, even though these individuals may have normal audiometric thresholds. These changes are more likely to be picked up by speech...