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Prognostic value of neutrophil-to-lymphocyte ratio in HPV-positive oropharyngeal cancer
The authors propose that high neutrophil-to-lymphocyte ratio (NLR) is associated with poor disease-free survival (DFS) in patients with human papillomavirus positive (HPV+) oropharyngeal cancer (OPC). This is a retrospective study that compared the outcomes of 43 patients treated for HPV+...
Validating a new international cholesteatoma classification – a necessary but challenging task
A European and Japanese joint consensus statement was published in 2017 which proposed a new cholesteatoma staging classification (EJS), with four stages. This follow-up publication aims to assess the internal and external validity of the staging system using existing prospectively...
Effect of COVID-19 on hearing and balance
Rhinological symptoms are cardinal features of COVID-19. However there have only been anecdotal reports on the involvement of the ear, the closest neighbour to the nose and throat. The aim of this study was ‘to assess the presence of persistent...
Complications associated with intra-tympanic steroid injections for sudden sensorineural hearing loss
Around 15,000 people in the UK experience a sudden sensorineural hearing loss (SSNHL) each year, and in the majority of cases the cause is unknown. Treatment options for idiopathic SSNHL include various modalities of steroid treatments which have known limitations...
Blood-sampling prognostic predictors for Bell’s palsy
Bell’s palsy is generally defined as an acute-onset unilateral idiopathic mononeuropathy in the facial nerve. It is of unknown aetiology, however, inflammation is considered a major cause. Electroneurography assessing nerve excitability is the most reliable examination for predicting prognosis of...
Systematic review and meta-analysis showing benefit of cochlear implantation in adults with single-sided deafness
This article presents results of a systematic review and meta-analysis to further investigate the impact of unilateral cochlear implantation (CI) in adults with single-sided deafness (SSD) with regards to speech perception in quiet and noise, tinnitus, sound localisation and quality...
Virtual vestibular rehabilitation (VR) is as effective as in-person VR
The effectiveness of vestibular rehabilitation (VR) for patients with several vestibular disorders is well established. Access for in-person clinic-based VR is however patchy and limited. To widen access, offering VR via virtual platforms is increasingly being adopted. The authors conducted...
Extranodal extension following surgical resection of HPV-positive oropharyngeal cancer – is adjuvant radiotherapy alone sufficient?
Human papillomavirus (HPV) is a known aetiological factor in oropharyngeal squamous cell carcinoma (OPSCC). HPV-positive OPSCC is recognised to have a more favourable prognosis than HPV-negative disease. Treatment deintensification for HPV+ OPSCC has therefore been an area of research focus...In conversation with Professor Claire Hopkins
There can be few ENT surgeons who have had such a pivotal role in the COVID pandemic as Claire Hopkins. She has been instrumental in changing the diagnostic criteria, and has been a frequent presence in the media, as Sean...Recalcitrant chronic rhinosinusitis: What to do next?
Whilst the majority of patients with chronic rhinosinusitis (CRS) will significantly improve with treatment, we are sometimes left with a ‘hard-core’ of nasal cripples who fail to improve despite our best efforts. How can we deal with these patients? Valerie...Tonsillectomy in adolescents
Tonsillectomy is one of the most common operations performed across the developed world. Salil Sood and Ray Clarke discuss the special considerations that apply when performing this procedure on adolescent patients. Tonsillitis in teenagers can be exceptionally painful and disruptive....
