You searched for "THRIVE"
High dose betahistine as effective as, but slower acting compared to intratympanic dexamethasone in intractable Meniere’s disease
The management of intractable Meniere’s disease poses a complex conundrum to otolaryngologists. The focus of treatment is decreasing the severity and frequency of vertigo and tinnitus whilst trying to preserve hearing. Betahistine has been used for many years in the...
Chemo-radiation in elderly patients with head and neck cancers
Chemo-radiotherapy is the standard of care for organ preservation in stage three and four oropharyngeal cancer, prospective data on patients over 65 has not been available as they are usually excluded from randomised trials. This paper reviews the experience of...
Eustachian tube function before and after FESS
This is a prospective study from the UK looking at Eustachian tube dysfunction (ETD) in patients with chronic rhinosinusitis (CRS) undergoing surgery. Fifty-seven consecutive patients who had failed medical therapy and were scheduled for endoscopic sinus surgery completed SNOT-22 and...
The continued evolution of surgical techniques for bone anchored hearing devices
This paper is not the first, and is unlikely to be the last, to look at a variation on the current technique for inserting the percutaneous titanium bone-anchored component of a bone conduction hearing device. In less than a decade,...
Laryngopharyngeal reflux - would mucolytics help?
With laryngopharyngeal reflux (LPR) being such a common presenting complaint to ENT clinics, who would not want to have more, effective treatment options for patients suffering with this annoying condition? In their small randomised, controlled trial, Chae et al put...
Management of postoperative cholesteatoma
This prospective longitudinal observational study compared the ability of second-look surgery with that of surveillance using serial non-echo-planar diffusion-weighted imaging to detect residual cholesteatoma after canal wall-up mastoidectomy. A total of 34 patients were included in the study who underwent...
Hyperbaric oxygen therapy a treatment for sudden sensorineural hearing loss
Cochlear ischaemia has been postulated as one of the potential aetiologies for sudden sensorineural hearing loss. Hence, increasing oxygen delivery to the cochlea by hyperbaric oxygen therapy has been explored as a potential treatment to reverse hearing loss. The authors...
Long-term effectiveness of sleep surgery for obstructive sleep apnoea
n this study, 39 patients from Turkey with obstructive sleep apnoea (of varying severity) underwent an expansion sphincter pharyngoplasty. This operation was devised by Prof Kenny Pang in Singapore and involves using the palatopharyngeus muscle and partly relocating it laterally...
Olfactory disorders in COVID-19
This Turkish prospective longitudinal observational study evaluated olfactory disorders (OD) and recovery processes in patients with COVID-19 infection at three time points within the first month of diagnosis: time of diagnosis with positive PCR test; time of first negative PCR...
Identifying clinically useful salivary substitutes
This in vitro study analysed the efficacy of salivary substitutes used in the treatment of xerostomia following head neck irradiation. The researchers applied the products under evaluation onto a synthetic surface and onto cellular gingival models. The products were then...
Association between depression and survival in patients with head and neck cancer
Approximately 40% of patients develop major depressive disorder (MDD) during diagnosis and treatment for head and neck cancer (HNC). Depressive symptoms in these patients have a significant effect on their rehabilitation and survival. Given the small number of studies in...
