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Allergen immunotherapy and allergic rhinitis – EAACI guideline 2017

Allergic rhinitis (AR) is a common chronic childhood disease with considerable social burden and impact on quality of life, frequently necessitating treatment with various combinations of antihistamines and corticosteroids. The allergen immunotherapy (AIT), sometimes known as desensitisation therapy, can modify...

Allergic rhinitis, the usual suspects

Allergic rhinitis (AR) is characterised by allergen binding to IgE on mast cells and basophils and subsequent histamine, prostaglandine D2 (PGD2) and cysteinyl leukotrienes (cysLTs) release causing early-phase response. This is followed by late-phase response mediated by eosinophils. Other cells,...

Biologic therapies for chronic rhinosinusitis with nasal polyps: a new paradigm

Surgery for nasal polyposis has evolved significantly in the last 30 years, and now the medical management may be on the cusp of a revolution. Biologics using monoclonal antibodies to target specific immune pathways have introduced a paradigm shift in...

The Dilemma of Beethoven’s Deafness

Beethoven was one of the world’s greatest musicians, and his deafness is well known. Many details of his medical conditions are known, and various theories of his hearing loss have been proposed. Ludwig van Beethoven was born in 1770 in...

The curse of Sports Illustrated

“Not a supernatural curse, but a basic statistical concept of blinding simplicity.” What is ‘regression to the mean’? I am reliably informed that our former North American colonies publish a periodical known as Sports Illustrated (note, incidentally, the characteristically incorrect...

The Malawi Hearing Project

Rachael Collins, ENT trainee in the UK, and Mwanaisha Jauza Phiri, audiologist in Malawi, explore the challenges and innovations in delivering ear and hearing care (EHC) across Malawi. The Malawi Hearing Project, a partnership between QECH and Cambridge Global Health...

Mind the gap – developing a sustainable pipeline for hearing therapeutics

In this article, the authors describe three key challenges faced in developing hearing therapeutics. Collaboration between companies, sectors and disciplines will be key to finding solutions. The unmet need for therapies for hearing loss grows apace, with prevalence rising across...

COACH calls for participants

The Nottingham Clinical Trials Unit has renewed a call for volunteers to take part in its COACH programme. The UK-wide trail aims to generate evidence about the use of hearing aids.

Hearing Care, cognitive decline and dementia: A public health challenge, or an opportunity for healthy ageing?

Brian Lamb, OBE and Sue Archbold PhD, Hon LLD A new document from The Ear Foundation, launched at European Association of Cochlear Implant Users (EURO-CIU) annual general meeting in Poland, reviews the latest evidence on the association between hearing loss,...

Five gold medals for ENT surgeon

ENT&Audiology News history section editor, Katherine Conroy, represented Great Britain at this year’s World Transplant Games. Athletes from 51 countries participated in multiple sports from 18 - 22 August in Dresden, Germany.

Bill Gibson: Pioneering Bionic Ear Surgeon

Professor Bill Gibson is one of the great pioneers of inner ear surgery and the recent publication of his biography is a reflection of his remarkable life and career. Bill Gibson: Pioneering Bionic Ear Surgeon will be enjoyed by everyone...

Bad splits

This is a meta-analysis of reported risk factors of a ‘bad split’ in a sagittal split mandibular osteotomy. They identified 30 observational articles and therefore acknowledged it is based on low quality studies. It is compounded by the definition of...