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Genetic foundations of Ménière’s disease: changing the game

Sydney researchers reveal genetic roots of Ménière’s disease. Familial patterns and gene discoveries highlight autosomal inheritance in rare cases, transforming molecular insights. Ménière’s disease (MD) is a chronic disorder of the inner ear defined by clinical criteria of episodic vertigo...

Are upper respiratory symptoms and macroscopic changes in children always due to gastro-oesphageal reflux?

In children, symptoms such as chronic cough, wheezing, stridor, voice changes, persistent asthma and dental erosion are often presumed to be due to gastro-oesophageal reflux and empirical treatment with PPIs is offered. Usual investigations, such as a barium meal, gastroscopy...

Nasal allergies and OSA

The first day of June is the meteorological start of summer. As a moderately wet spring slowly blurs to (a damp UK) summer, we can look forward to holidays in the countryside, enjoying the changing pollen seasons from tree to...

Chronic cough hypersensitivity syndrome

We all have patients who give us a ‘heartsink’ feeling; for many of us, the coughing patient is exactly such a situation. In this overview, Bhaskar Ram and Sangeeta Maini outline their approach to diagnosis. Declan Costello, Editor. Introduction Chronic...

‘What does Sound Look like to You?’ Art competition

Artists are being put to the test to represent sound in a visual artform, as part of a competition hosted by the charity, Helping Uganda Schools, and supported by ENT & Audiology News and the Manchester City Art Gallery. Submissions...

The common frontal sinusotomy (Lothrop) and chronic rhinosinusitis

As our understanding of the pathophysiology of CRS evolves, so do our treatment strategies. It is accepted that in many cases, the main role of surgery is to allow better penetration of topical therapies to the sinus cavities. What, then,...

Managing CRS in pregnancy

An International team of experts from both sides of the Atlantic set out to perform a systematic review of the management of chronic rhinosinusitis in pregnancy. Despite a thorough search no scientific evidence was found that could form the basis...

CRSwNP, another monoclonal antibody

Interleukins 4, 5 and 13 were shown to be important factors in type 2 inflammation, which characterises chronic rhinosinusitis with nasal polyposis (CRSwNP). In CRSwNP non-responders and those who recur short after-surgery monoclonal antibodies might be an answer. Examples include...

A new hope for post-COVID olfactory loss?

Does anyone remember COVID? It seems that what happened between 2019 and 2021 is all but forgotten about. Aside from it cropping up on news feeds occasionally and a few out-of-date automated phone messages that start off with ‘During the...

Patients with severe uncontrolled CRSwNP respond to biologics in the real world

Clinical trials have demonstrated that biologics are effective in treating patients with chronic rhinosinusitis with nasal polyps (CRSwNP). This multicentre (15 tertiary care centres in France) observational prospective cohort study aims to examine the effectiveness of biologics in treating CRSwNP...

Dr KJ Lee: From Penang to Presidency of the AAO-HNS… and beyond!

Anyone who’s ever stopped to wonder about the personalities behind well-known names in ENT will enjoy Keyu Liu’s article on Dr KJ Lee, rich with stories of his travels, inspirations, and personal philosophies, alongside his momentous achievements. If you’ve experienced...

Timing of surgery in chronic rhinosinusitis: does it matter?

While many patients with chronic rhinosinusitis respond to medical treatment, some do not. The next step for these patients is surgery, but how soon should this be offered? Sooner rather than later seems to be the answer, as Claire Hopkins...