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Updates on current evidence for biologics in chronic rhinosinusitis
For a comparatively short piece, this article manages to pack in a lot of important information about a complex emerging area of rhinology – immunologically targeted therapy (biologics). Immunologically targeted therapy is a rapidly progressing and expanding domain which is...
To montelukast or not to montelukast
Both histamine and cysteinyl leukotrienes play an important role in both seasonal allergic rhinoconjunctivitis (SARC) and asthma. A combination therapy against both was shown to give benefit both in vitro and in vivo. Authors wanted to test the efficacy of...
Advances in neural stimulation of the auditory pathway
This article reviews the use of neuroprosthetic devices such as cochlear and auditory brainstem implants (ABI) to stimulate the auditory pathway, discussing the successes, limitations and advances in this area. Currently, neuroprosthetic devices deliver electrical impulses to the cochlear nerve...
The association between pregnancy and otosclerosis could be due to psychosocial factors around parenthood rather than biological factors
The association between pregnancy and otosclerosis is controversial. If pregnancy physiologically increases the likelihood of otosclerosis progression, then one would expect that there would be a difference between male and female patients with regards to whether having children affects how...
Predicting the need for salvage laryngectomy
The treatment of laryngeal cancer has seen a shift towards organ preservation strategies with non-surgical treatment offering equivalent survival outcomes. Nonetheless, salvage total laryngectomy (SLT) remains an important curative management option in cases of treatment failure or recurrence. The authors...
Neuromodulation in drug resistant epilepsy
Treatment of epilepsy can be considered generally as medical or surgical. Anti-epileptic drugs achieve a five-year seizure freedom in 54-70% patients. It is estimated that 50-90% of patients with drug-refractory epilepsy may not be candidates for resective surgery. For example,...
Endoscopic stapes surgery - pearls and pitfalls
Endoscopic ear surgery has gained popularity in recent years with wide panoramic visualisation of the operative field one of its key strengths. This article summarises the approach, set-up and outcomes of patients undergoing endoscopic stapes surgery. A key step during...
Combination PPI and intralesional steroid treatment for recurrent laryngeal granuloma
The existence of a wide range of treatments for recurrent laryngeal granulomas (repeat surgery, high-dose proton pump inhibitor (PPIs), surgery with botulinum toxin injection, botulinum toxin injection alone, etc) is a testament to the refractory nature of this condition, with...
Long-term effectiveness of sleep surgery for obstructive sleep apnoea
n this study, 39 patients from Turkey with obstructive sleep apnoea (of varying severity) underwent an expansion sphincter pharyngoplasty. This operation was devised by Prof Kenny Pang in Singapore and involves using the palatopharyngeus muscle and partly relocating it laterally...
Balloon Eustachian tuboplasty – is it time to start doing it in children?
Given the potential applications for balloon Eustachian tuboplasty (BET) in children, its uptake in most centres has been slow. The reasons for this are multifactorial. There are technical issues – the feasibility of obtaining the correct size balloon and manoeuvring...
An advance in imaging for sinonasal tumours?
Benign sinonasal growths are incredibly common, and malignant sinonasal growths thankfully rare. We know that malignant tumours often present late, and the imaging can sometimes be misleading, so the authors here compare using diffusion weighted imaging (DWI), dynamic contrast enhanced...
