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Long-term results for dupilumab are very promising!
Eosinophilic chronic rhinosinusitis (eCRS) is complicated by frequent early and aggressive recurrence of polyps after both medical and surgical treatment regimes. Dupilumab is an anti-IL-4/IL-3 receptor monoclonal antibody and has been previously studied in the SINUS-52 study, with an observation...
Going online with dysphagia practice: potential for innovation post pandemic
Telepractice is perhaps the most widespread service innovation to have received such rapid uptake across health systems globally. Disciplines that started to adopt telehealth prior to the pandemic found themselves at the forefront of a seismic shift to delivering healthcare...Erasmus Darwin and the larynx – but why is it where it is and when?
Charles Darwin’s grandfather was not only on to where we all came from by the end of the 18th century, but dared to declare it in verse whilst resident in Lichfield Cathedral Close. This needed exceptional temerity, since not only...
Options for the endoscope and acquired cholesteatoma
This was a thought-provoking article examining the reasons why the authors believe that the endoscope is enabling an improved understanding of acquired cholesteatoma and its management. They describe in depth the ventilation pathways of the middle ear, and how they...
Does albumin have an effect on nasal polyposis?
Sometimes a short paper catches your eye! What causes chronic rhinosinusitis? What causes polyps? Fungi? Biofilms? Allergy? Maybe the lack of albumin? The two authors of this short paper present data that may suggest that the lack of albumin can...
Risk factors for pharyngocutaneous fistula after laryngectomy
Pharyngocutaneous or salivary fistula is a feared complication following laryngectomy, causing significant morbidity, prolonged hospital inpatient stay / cost and mortality. Previous radiotherapy / chemoradiotherapy is a well recognised risk factor and leads many surgeons to recommend onlay pectoralis major...
The theory of everything (tonsil)?
Tonsil sepsis can manifest as acute tonsillitis, a peritonsillar abscess (PTA) or rarely as an intra-tonsillar (ITA) abscess. Whilst the management of these conditions is familiar to ENT surgeons from early in training, perhaps little attention has been paid to...
Coupler microvascular anastomoses: how good?
This paper is written by a group of reconstructive surgeons and a school of computing. The study used computational fluid dynamics to model blood flow through idealised sutured and coupled vessels, to investigate if differing anastomotic techniques affect intravascular blood...
