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Dupilumab prospective RCT for CRSwNP, a multinational trial of 60 patients with a 16-week CT follow-up
This transcontinental work describes a randomised, double blind, placebo controlled parallel group study over a 16-week period, assessing 60 patients with CRSwNP by CT scan scores. All patients had a four-week period of intranasal corticosteroids followed by randomisation to add...Matthew Clark: full-time otologist, spare-time sculptor
Drilling a temporal bone may seem like torture to some trainee surgeons. To others it is but a stepping stone to something altogether grander... I took Art A-level a year early so as not to interfere with the ‘important subjects’,...
Introduction to Aural Rehabilitation Serving Children and Adults with Hearing Loss - Third Edition
As the name indicates, this book deals with the bread and butter of audiologists or at least what should be our bread and butter. We work with changing people in changing environments, therefore, along with an acute understanding of technology,...
Updates on current evidence for biologics in chronic rhinosinusitis
For a comparatively short piece, this article manages to pack in a lot of important information about a complex emerging area of rhinology – immunologically targeted therapy (biologics). Immunologically targeted therapy is a rapidly progressing and expanding domain which is...
How to improve olfaction and enhance quality of life after laryngectomy
Total laryngectomy diverts airflow away from the nose and, hence, olfaction is greatly impaired. Undoubtedly, this affects quality of life in terms of loss of taste and flavour. Surgery and devices to re-establish airflow into the nose can be difficult...
Budesonide nasal irrigation for chronic rhinosinusitis: is it effective and safe?
Budesonide respules used in nasal irrigations as part of chronic rhinosinusitis management are usually at a dose of 0.25 mg to 2 mg, which is substantially higher compared to budesonide nasal spray, typically ranging from 64 to 256 micrograms. Hence,...Jacobsen’s organ
The vomeronasal organ (VNO) was not, in fact, first described by Jacobsen in 1809, but by Frederik Ruysch (1638–1731), the noted Dutch anatomist. He had an absolute passion for embalming, and his ‘Cabinet of Curiosities’ in Amsterdam was acknowledged as...
Milestones profile for children with cochlear implant
Over the last eight years, Nottingham auditory implant programme have developed and validated a profile of auditory milestones for use with children receiving bilateral cochlear implants under the age of two years. The structure of the Nottingham Auditory Milestones profile...
Button batteries – how can we reduce harm to children?
This article explores the history of button batteries and how clinicians and industries alike could reduce the harm to children following ingestion. Following ingestion, if lodged, button batteries cause an alkaline reaction leading to necrosis of mucosa. Significant oesophageal injury...
