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Case study suggesting mtDNA mutation as a tinnitus factor: ND1:m.3394T>C

Konadath et al report a genetic case study of a 24-year-old female experiencing reduced hearing sensitivity and tinnitus along with a blocked sensation in her right ear, sudden onset one year prior with no other otological complaints. Standard audiometry along...

Bell’s palsy – antivirals and steroids for all?

The role of antiviral medications in the treatment of Bell’s palsy remains somewhat controversial. Antivirals alone do not appear to be helpful, whereas numerous studies have shown that corticosteroids improve the chance of a full recovery compared to placebo. What...

Virtual vestibular rehabilitation (VR) is as effective as in-person VR

The effectiveness of vestibular rehabilitation (VR) for patients with several vestibular disorders is well established. Access for in-person clinic-based VR is however patchy and limited. To widen access, offering VR via virtual platforms is increasingly being adopted. The authors conducted...

Temperature-controlled radiofrequency treatment of the nasal valve confers sustained benefit

Aiming to investigate long-term efficacy and safety (three years post treatment), this was an extension of a previous multicentre, prospective, single-blinded, randomised controlled trial that investigated the effectiveness and safety of temperature-controlled radiofrequency treatment (TCRF) to the nasal valve (NV)...

Patients with severe uncontrolled CRSwNP respond to biologics in the real world

Clinical trials have demonstrated that biologics are effective in treating patients with chronic rhinosinusitis with nasal polyps (CRSwNP). This multicentre (15 tertiary care centres in France) observational prospective cohort study aims to examine the effectiveness of biologics in treating CRSwNP...

EBM Stats Calc: there’s a stat for that

Quantifying the value of a specific test or intervention for a patient is no easy feat. Even when the value of a given test or intervention has been established, there may be additional case-specific factors to consider that are not...

Communicating with patients in 
‘Plain English’

Physicians have long been accused of using unnecessarily complicated language and impenetrable jargon as a way of maintaining their status, prestige and high earnings-potential, bamboozling the public and excluding them from meaningful discussion as part of what George Bernard Shaw...

Thyroid ultrasound elastography: does nodule stiffness predict malignancy?

Approximately 50% of the general population has a thyroid nodule while 5-15% of these are malignant [1]. A major challenge, therefore, is how to detect the malignant nodules for appropriate, timely treatment and avoid unnecessary, costly investigations for the remainder....

Hidden genetic disorders in children that may present to the otolaryngologist

Background Among the many hundreds of children presenting to the otolaryngology clinic are a few whose symptoms are due to an underlying genetic condition. In most cases the underlying syndrome is obvious and has already been diagnosed, such as the...

Surgical management of sleep disordered breathing

Snoring and sleep-disordered breathing are often described as multi-level problems, and different surgical procedures are required to treat the various sites of airway narrowing and/or collapse. Jonathan Hobson gives us an eloquent run-through the various options available to the ENT...

International Federation of Head and Neck Oncologic Societies (IFHNOS): its programmes and impact on head and neck cancer worldwide

In the first article of this edition, we introduce IFHNOS, which has created a major impact on the landscape of head and neck cancer treatment and education over the past quarter of a century by offering a global platform amongst...

The role of macrolide antibiotics in chronic rhinosinusitis

The use of long-term antibiotics in the treatment of chronic rhinosinusitis is a contentious issue, not only because of the increasing problem with antibiotic resistance but also because of the potential cardiac risks, including sudden death. In this article, Anders...