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3242 results found

Expanding the role of FNA in thyroid nodule decision-making

Papillary thyroid cancer, the commonest histological type, has been extensively reported as having BRAF proto-oncogene mutations (most commonly the V600E mutation). There is great interest in BRAF as a molecular marker, particularly as a prognostic factor that may guide the...

Modernising scientific careers and audiology in the United Kingdom

Modernising Scientific Careers (MSC) is an education and training strategy for 51 disciplines in healthcare science within the National Health Service (NHS) in the United Kingdom (UK). Some of these disciplines lacked clear training routes as well as registration opportunities...

Breath – The New Science of a Lost Art

‘Popular science’ has become a discrete genre in the publishing world and there seems to be an insatiable desire for well-written books that explain the mysteries of human physiology to ‘lay’ readers. This is one such book, and the author...

Screening for hearing loss in primary care

Hearing impairment is one physical disability that is increasing in prevalence in society in general, and in older adults in particular. Approximately 34 to 36 million Americans report suffering from some degree of hearing impairment with the number rising to...

The astronomer’s nose: Tycho Brahe’s controversial prosthesis

Tycho Brahe (1546-1601) is a familiar and colourful figure in the history of science. The immense quantity of data he collected during his lifetime would enable the work of Johannes Kepler and has gained him admission to the astronomical pantheon....

What is Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE)?

THRIVE is a physiological mechanism for oxygenating and ventilating patients who are under general anaesthesia and who have diminished or absent respiratory effort [1]. Classical ventilation requires bulk flow of gases into and out of the lungs driven by chest...

Interleukins, cilia and polyps

Interleukins (ILs) including IL13 (Th2 cytokine) are inflammatory mediators and their role in asthma has been detailed before. This study explores IL13 receptor expression in chronic rhinosinusitis with nasal polyps (CRSwNP). The authors investigate protein and mRNA expression levels of...

Enhancing performance and well-being for surgeons: the science of life coaching

Life coaching has emerged as a powerful personal and professional development tool, particularly for individuals navigating high-stakes environments. Life coaching emphasises self-awareness, self-management and self-efficacy, including establishing desired outcomes, goal setting and developing skills and action plans to achieve them....

Aspirin desensitisation for aspirin-exacerbated respiratory disease (AERD)

In this article, the authors describe the importance of identifying aspirin-exacerbated respiratory disease in patients with chronic rhinosinusitis refractory to standard medical treatment. This can then open the door to considering aspirin desensitisation treatment which, in their hands, has proven...

Hearing care systems in Europe – can we do more?

52 million Europeans experience hearing loss but many don’t find their way to professional hearing care. Lidia Best looks at strategies to improve the uptake of amplification at a national level [1]. With rising numbers of people experiencing hearing loss,...

Treatment of internal carotid artery blowout with embolisation and bypass grafting (nasopharyngeal carcinoma)

Carotid artery blowout syndrome (CBS) occurs when there is rupture of the carotid artery causing massive epistaxis and bleeding through the oral cavity caused by tumour invasion, surgery, radiotherapy, or infection. This article proposes a revascularisation strategy for internal carotid...

Systematic review and meta-analysis showing benefit of cochlear implantation in adults with single-sided deafness

This article presents results of a systematic review and meta-analysis to further investigate the impact of unilateral cochlear implantation (CI) in adults with single-sided deafness (SSD) with regards to speech perception in quiet and noise, tinnitus, sound localisation and quality...