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Patients with severe uncontrolled CRSwNP respond to biologics in the real world

Clinical trials have demonstrated that biologics are effective in treating patients with chronic rhinosinusitis with nasal polyps (CRSwNP). This multicentre (15 tertiary care centres in France) observational prospective cohort study aims to examine the effectiveness of biologics in treating CRSwNP...

Magnetic resonance imaging (MRI) head without general anesthesia in children

‘Physician heal thyself’: this biblical proverb has an increasing importance in modern healthcare systems, especially when we consider the rising incidence of physical and mental burnout amongst all staff. Musculoskeletal disorders are increasing – according to the Work-Related Musculoskeletal Disorders...

Extranodal extension following surgical resection of HPV-positive oropharyngeal cancer – is adjuvant radiotherapy alone sufficient?

Human papillomavirus (HPV) is a known aetiological factor in oropharyngeal squamous cell carcinoma (OPSCC). HPV-positive OPSCC is recognised to have a more favourable prognosis than HPV-negative disease. Treatment deintensification for HPV+ OPSCC has therefore been an area of research focus...

Epley manoeuvre angles

Posterior canal benign paroxysmal positional vertigo (PC-BPPV) is a common vestibular cause of dizziness regularly encountered in the outpatient clinic. The condition is often diagnosed with a positive Dix-Hallpike manoeuvre (DHM) – turning the patient’s head 45 degrees to the...

EBM Stats Calc: there’s a stat for that

Quantifying the value of a specific test or intervention for a patient is no easy feat. Even when the value of a given test or intervention has been established, there may be additional case-specific factors to consider that are not...

Hidden genetic disorders in children that may present to the otolaryngologist

Background Among the many hundreds of children presenting to the otolaryngology clinic are a few whose symptoms are due to an underlying genetic condition. In most cases the underlying syndrome is obvious and has already been diagnosed, such as the...

St Æbbe the Younger of Coldingham, patron saint of the nose

Stories of the saints are often rather dark and unpleasant – and this is certainly the case with St Æbbe, as we hear from our roving historian, John Riddington Young. In two previous articles, we have discovered the fascinating stories...

Communication Disorders: a combined discipline of audiology and speech and language pathology – the Israeli perspective

Liat Kishon-Rabin provides an excellent summary of audiology training in Israel, encapsulating the development of audiology services in the country. Readers will be intrigued by the systematic approach taken to its development, and its pairing with speech and language pathology....

Measuring the pitch and loudness of tinnitus

Matching the characteristics of tinnitus Many researchers and clinicians have explored the subjective nature of tinnitus by asking people with tinnitus to adjust a sound so that it matches their tinnitus in some way. This can be useful both for...

Lyric 24/7 hearing: could it help those with tinnitus?

About Lyric Hearing Since its launch in 2008, Lyric represents the first and only device of its kind establishing a new category of hearing solution: 24/7 extended wear. Lyric is placed several millimetres within the ear canal, near the tympanic...

Hearing in middle-age: hearing impairment, tinnitus and hearing aid use in UK adults

Hearing loss has a well-documented adverse impact on emotional, social and physical well-being. In this article, Dr Piers Dawes from the University of Manchester gives an insight into his team’s recent work analysing the very large UK Biobank data set,...

Branchio Oto Renal syndrome

Branchio Oto Renal Syndrome (BOR) is an autosomal dominant disorder with branchial, otologic and renal manifestations. The presence of clinical signs varies among and within affected families. Three causative genes for BOR syndrome have been reported thus far: EYA1, SIX1...