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Endotypes in chronic rhinosinusitis: clinical relevance

Identifying endotypes enables personalised therapies that target specific pathophysiological processes, potentially resulting in better treatment outcomes for patients. The contemporary model of chronic rhinosinusitis (CRS) pathogenesis revolving around endotype, in combination with an expanding toolbox of diagnostics and therapeutics, enables...

Managing CRS in pregnancy

An International team of experts from both sides of the Atlantic set out to perform a systematic review of the management of chronic rhinosinusitis in pregnancy. Despite a thorough search no scientific evidence was found that could form the basis...

Is Dymista® useful for paediatric allergic rhinitis?

Allergic rhinitis (AR) affects up to 14.6% of the paediatric population. Whilst a recent Cochrane review has considered the evidence for intranasal corticosteroids as `weak and unreliable’ in paediatric AR, this product is a novel formulation combining Fluticasone and Azelastine...

Patients with severe uncontrolled CRSwNP respond to biologics in the real world

Clinical trials have demonstrated that biologics are effective in treating patients with chronic rhinosinusitis with nasal polyps (CRSwNP). This multicentre (15 tertiary care centres in France) observational prospective cohort study aims to examine the effectiveness of biologics in treating CRSwNP...

Professor Hugh Montgomery

BACO International 2018 has some truly astonishing speakers, but perhaps none more astonishing than Hugh Montgomery. His friend and colleague David Howard chatted with him about some of his diverse interests. Prof Hugh Montgomery. Prof Hugh Montgomery will be giving...

Have we reached our limits in endoscopic skull base surgery?

As being an anterior skull base surgeon becomes the aspiration of many ENT trainees, Professor Nicolai gives his personal insights into the future for this exciting subspeciality. Having been directly involved in the evolution of transnasal endscopic surgery (TES) since...

Reflux – diagnostic tools and special considerations in singers

Depending on your point of view, laryngopharyngeal reflux (LPR) is either ubiquitous or is over-diagnosed. Are singers more prone to LPR? What are the best tests? Mark Watson and Jane Shaw tell us more. Laryngopharyngeal reflux (LPR: the backflow of...

Pollen forecasting apps: don’t worry, bee happy!

Hay fever sufferers rejoice! Around a fifth of people in the UK self-report to having hay fever (allergic rhinitis). In the majority of cases, this is thought to be a sensitivity to grass pollen. Symptoms may present as nasal congestion,...

The power of mentoring

What is a mentor, and what are the benefits for mentee and mentor? Emma Stapleton and Rohma Abrar, mentor and mentee respectively, explain. The term ‘mentor’ is derived from Homer’s Odyssey, in which the goddess Athena, disguised as Mentor, guides...

Genomic testing for deafness and its implications

Gene therapies for hearing loss are rapidly advancing and will be transitioning to clinical practice. Here, the authors explain why clinicians involved in managing these disorders need to be aware of these advances. Genomic testing in England was significantly reconfigured...

Which scan for children with bilateral sensorineural hearing loss? Keeping the debate going…

There have been years of debate about the appropriate imaging strategy for children with bilateral sensorineural hearing loss. For those children undergoing cochlear implant surgery, CT may provide some assistance to surgical planning, although this is not necessary in children...

Sex and the Nose

For regular attentive readers of our little magazine, JRY will need no introduction. The word ‘polymath’ barely does him justice: a Colonel in the Medical Corps with an MPhil in poetry and apparently one of the “50 coolest people in...