You searched for "genes"
N-acetylcysteine may have a role in the protection of cochlear hair cells
Gentamycin is an aminoglycoside antibiotic which is widely used throughout the world, despite its ototoxic potential. It therefore seems wise to continue the search for accessible otoprotective agents. The aim of this study was to clarify the potential protective role...The first nine months: why early hearing matters more than ever
Why 1-3-6 and 9? They are arguably crucial intervention stages. Here, new science is explored which weaves together the threads of early intervention. Imagine a newborn gazing at their caregiver’s face, hearing their voice and feeling the rhythm of their...Changing the face of global health: short-term surgical trips
With the growth of global health awareness, global surgery has emerged as a key focus area. This article examines short-term surgical trips (STSTs) as one of the ways used to address some of the gaps in global surgery. It demonstrates...
Blindness after orthognathic surgery
This is a case report and review of the literature of this rare, but well recognised alarming complication. The authors discuss the possible mechanisms, suggesting that it does not arise from a direct injury to the optic nerve and is...
Long-term outcomes after (adeno) tonsillectomy
Patient-reported outcome measures (PROMs) are used increasingly to fill an ‘evidence gap’ where healthcare rationing threatens particular treatments. Tonsillectomy is a long-established and effective treatment for recurrent tonsillitis and obstructive sleep apnoea (OSA) in children. The T-14 outcome measure examines...
Malignant craniopharyngiomas
Craniopharyngiomas are successfully managed with surgery and / or adjuvant chemoradiotherapy. The transnasal endoscopic route has become increasingly utilised in the management of these challenging tumours. This paper reviews 23 cases from the literature of the rarely reported malignant transformation....
Maxillomandibular advancement and airway morphology
This is a cadaveric study comparing alterations in airway volume. Seven advancements of the maxillomandibular complex were undertaken, each with a 2 mm incremental advancement being scanned with a total of eight scans per cadaver. They showed that comparisons between...
Lateral wall augmentation for patulous eustachian tube
The problem more commonly attributed to the eustachian tube is lack of its patency rather than it being unduly patulous. This lesser recognised condition is due to loss of peritubal fat volume resulting in concavity of the lateral wall and...
Robot controlled mastoid surgery!
This is a fascinating piece of work by a Korean team developing a human-robot collaborative control. Their model uses image guidance surgery to locate the drill tip’s position. Important structures can be highlighted – in this case the facial nerve....
Concussion and isolated mandible fractures – are we asking the right questions?
Concussion and isolated mandible fractures – are we asking the right questions? The mandible is one of the most commonly fractured craniofacial bones. A significant force is required to bring this about. Hence the authors hypothesised that concussion after a...
3D printed temporal bones for drilling are here!
It was only a matter of time before the 3D printer was used to help us with simulated temporal bone (TB) drilling. This group printed three paediatric TB models and evaluated their quality. They were found to be of ‘high...
