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The role of macrolide antibiotics in chronic rhinosinusitis
The use of long-term antibiotics in the treatment of chronic rhinosinusitis is a contentious issue, not only because of the increasing problem with antibiotic resistance but also because of the potential cardiac risks, including sudden death. In this article, Anders...CI2023
Dr Andrea Warner-Czyz, Assistant Professor in communication disorders, School of Behavioral and Brain Sciences, UT Dallas, USA. Cochlear implant clinicians and scientists from around the world gathered in June for the annual clinical research conference of the American Cochlear Implant...FDA Approved Lenire Expands Number of US Clinics
Neuromod Devices, the medical technology company that developed tinnitus treatment device, Lenire, has partnered with an additional 24 new US clinics to address the significant demand for the FDA Approved tinnitus treatment device.Can we prevent chronic rhinosinusitis?
The old adage ‘prevention is better than cure’ is considered by Professor Hopkins in respect to chronic rhinosinusitis, a condition affecting around 10% of the adult population and associated with huge impact on quality of life and economic cost. A...Biologic therapies for chronic rhinosinusitis with nasal polyps: a new paradigm
Surgery for nasal polyposis has evolved significantly in the last 30 years, and now the medical management may be on the cusp of a revolution. Biologics using monoclonal antibodies to target specific immune pathways have introduced a paradigm shift in...
CRSwNP, another monoclonal antibody
Interleukins 4, 5 and 13 were shown to be important factors in type 2 inflammation, which characterises chronic rhinosinusitis with nasal polyposis (CRSwNP). In CRSwNP non-responders and those who recur short after-surgery monoclonal antibodies might be an answer. Examples include...
Chronic phase of concussion and stability of gaze
It has been known that vestibular symptoms can persist for several months after concussion. The authors designed this study to assess the effect of chronic concussion (more than one year) on gaze stability and the relationship between deficits in gaze...
Does ipratropium responsiveness predict posterior nasal nerve neurectomy/ablation outcomes in chronic rhinitis?
This study’s main objective was to assess whether topical ipratropium response is predictive of subsequent response to posterior nasal nerve (PNN) interventions, including surgical neurectomy or in-office ablation, in chronic rhinitis (CR). This is a retrospective study of adult patients...
The effect of cocaine or adrenaline dressing during endoscopic sinus surgery
A randomised controlled study of 37 patients took place that underwent endoscopic sinus surgery for chronic rhinosinusitis and received adrenaline or cocaine-soaked patties. The study showed no difference in the mean surgical field scores between adrenaline and cocaine sides. Adequate...
Do we need to intervene after complications of acute sinusitis in children?
omplications of acute sinusitis in children are not uncommon and some are managed surgically. The authors of this paper reviewed their experience of subsequent chronic rhinosinusitis (CRS). Nine of 86 patients required surgery in the 12 months after their initial...
Is there increased cardiovascular risk with macrolide antibiotics?
This month’s Ed’s Choice delightfully reviews the potential cardiovascular consequences of long-term macrolide use in the treatment of chronic rhinosinusitis. This used to be one of my ‘go-to’ topics of conversation at home after a bad day at work, although...
