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Intratympanic steroids - to give or not to give?

The treatment of idiopathic sudden sensorineural hearing loss (ISSNHL) is controversial and different modes of steroids have been tried without any universal consensus. Various authors have reported combined oral and intratympanic steroid therapy in SSNHL, with consistent results in several...

Should we be doing earlier MRIs in sudden sensorineural hearing loss?

There is recognised variation between ENT departments in exact imaging protocols for the workup of idiopathic sudden sensorineural hearing loss (ISSNHL) but a routine MRI to exclude retrocochlear pathology is standard, usually following immediate treatment with oral +/- intratympanic steroids....

Are we screening enough? Genetics in adult-onset sensorineural hearing loss

Sensorineural hearing loss (SNHL) in adults can be a result of multiple factors such as age, noise exposure and autoimmune pathology. In a group of patients, no cause is identified and the SNHL is treated as idiopathic. Authors evaluate the...

Sudden sensorineural hearing loss – who will get better?

Idiopathic sudden sensorineural hearing loss (ISSNHL) is a rare but potentially devastating condition. For patients presenting with this condition, prognosis is of paramount importance. Wu et al begin to address this issue by retrospectively studying 17 potential prognostic factors for...

Vascular disease and sudden sensorineural hearing loss

Oussoren et al performed a systematic review and meta-analyses of current literature on the above topic: specifically, cardiovascular risk factors for developing idiopathic sudden sensorineural hearing loss (iSSNHL), the presence of white matter hyperintensities in patients with iSSNHL and the...

Complications associated with intra-tympanic steroid injections for sudden sensorineural hearing loss

Around 15,000 people in the UK experience a sudden sensorineural hearing loss (SSNHL) each year, and in the majority of cases the cause is unknown. Treatment options for idiopathic SSNHL include various modalities of steroid treatments which have known limitations...

Does salvage treatment in sudden sensorineural hearing loss work?

Many treatment strategies for sudden sensorineural hearing loss (SSNHL) have been discussed, but the high spontaneous recovery rate (32-65%) of idiopathic SSNHL and differing treatment guidelines make comparing outcomes difficult. Systemic steroids are the most common first-line therapy with significant...

Recruitment of Sudden Hearing Loss Patients for Clinical Trial: Novel Compound AC102 Outperforms Corticosteroids Preclinically

While corticosteroids are widely used to treat Sudden Sensorineural Hearing Loss (SSNHL), there is still no therapy with proven efficacy and regulatory approval for this debilitating condition.

Laryngeal Function and Voice Disorders

This is a detailed, 323-page resource covering laryngeal function and voice disorders, basic science and clinical assessment. Spanning nine chapters, the authors cover the anatomy and physiology of phonation, survey of voice disorders, voice diagnostics, acoustic analysis, aerodynamic analyses, endoscopy...

Cerebrospinal Fluid Rhinorrhea: Comprehensive Guide to Evaluation and Management

Cerebrospinal Fluid Rhinorrhea: A Comprehensive Guide to Evaluation and Management stands out as a vital resource for professionals in otolaryngology, neurosurgery, ophthalmology, neurology, and radiology. This comprehensive guide covers an array of CSF leak causes, offering in-depth insight into their...

EMG and unilateral vocal fold palsy

The authors studied the diagnostic and prognostic value of laryngeal electromyography (LEMG) in adults with unilateral vocal fold palsy. The study included 61 patients who were tested on average seven months after their palsy (4-11 months). In most cases the...

Blood type and epistaxis

In this Turkish study, the authors attempted to determine if there was an association between ABO blood type and epistaxis. They looked at 359 epistaxis admissions at the same hospital over a three-year period. Only patients with idiopathic epistaxis were...