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A single blinded RCT comparing triamcinolone with 5-FU treatment for keloid scars

This single blinded RCT compared 43 patients with 50 symptomatic keloids that were randomised to two matched groups of 25 scars, receiving either 5-fluorouracil (5-FU) or current first line treatment, triamcinolone (TAC). The surgeon administering the injectable treatments was unblinded,...

Hearing disability questionnaires

This is a very interesting study concerning the validity and readability of 10 hearing disability English language questionnaires available for clinical use. The questionnaires were assessed against the World Health Organisation’s International Classification of Functioning, Disability and Health framework (WHO-ICF)....

Radiological diagnosis of mastoiditis in patients screened for acoustic neuroma

Magnetic resonance imaging is the ‘gold standard’ for screening patients suspected to have acoustic neuroma. Various abnormalities are picked up through this investigation, one of which, not uncommonly reported, is mastoiditis. This requires referral to otolaryngology and further evaluation. In...

eNOS and OME

The pathophysiology of otitis media with effusion (OME) is multifaceted. The authors tackled the nitrous oxide (NO) and platelet activating factor (PAF) pathways and the genetic polymorphism of endothelial nitrous oxide synthetase (eNOS). DNA analysis by PCR and restriction fragment...

Reducing readmission rates after transsphenoidal pituitary surgery

This retrospective study provides an outpatient care pathway to screen and manage delayed hyponatremia which the study identified as the primary cause of readmission following transsphenoidal pituitary surgery. Of the 303 patients who were studied, 27 were readmitted within 30...

Balloon eustachian tuboplasty and inferior turbinectomy

This Taiwanese prospective case-control study looked at concurrent inferior turbinectomy (via submucosal turbinectomy) and balloon eustachian tuboplasty on symptoms related to eustachian tube dysfunction. A total of 50 patients who underwent inferior turbinectomy with balloon eustachian tuboplasty were recruited prospectively...

What to do if adenotonsillectomy does not cure sleep apnoea in children?

This article reviews the management of children with persistent obstructive sleep apnoea (OSA) following adenotonsillectomy (AT). Risk factors for patients to have persistent disease include obesity, being Afro-Caribbean and existing co-morbidities such as craniofacial and neuromuscular disorders. Initial assessment of...

Clinical assessment in OSA

This paper divides the assessment up into anatomical (nasal and oropharyngeal), endoscopic and imaging. It points out the salient features to look out for in OSA patients with regards the nasal valve and also oropharyngeal anatomy, with tonsil hypertrophy grading...

Does turbinoplasty outcome vary in the presence of allergic disease?

This well organised study from Australia looks at inferior turbinoplasty outcomes in patients with allergy and non-allergic rhinitis who have become refractory to medical treatment. There were 190 patients undergoing turbinoplasty with or without septoplasty assessed in this case-control study...