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Precision and personalised genomic and epigenomic medicine in audiology/hearing loss

A detailed look at the pathogenesis of acquired hearing loss due to exposure to ototoxicity during pregnancy or shortly after birth. Insights from genomic medicine have shown that, along with environmental factors causing epigenetic alterations, hearing loss may be caused...

Fall prevention in the elderly population

A fall in later life can have a catastrophic impact on a person’s quality of life. Lilian Felipe explains how falls prevention programmes and vestibular rehabilitation can help.

In conversation with George Browning, author of Browning’s Audiology for Clinicians

Professor George Browning. It is one of those superbly bright August mornings in London’s West End. It gives Lamb’s Conduit Street, where I’m meeting George Browning, an almost timeless feeling. The café we meet at is bustling and noisy, and...

Advances in laryngeal surgery

We are seeing many advances in laryngology: from the lab, from equipment manufacturers and from developments in surgical techniques. The field of laryngology has been under constant change in recent years, with the introduction of new technologies and research. The...

Genetic discovery using animal models: presbyacusis

By their very nature, late-onset hereditary disorders offer a large window of opportunity for therapeutic intervention. However, before we can begin to think about strategies we need knowledge of the genetics and pathology underlying the condition. In this article we...

The changing spectrum of cancer of the oropharynx: dilemmas and future directions

The association of HPV in oropharyngeal cancer has identified a ‘new disease’, with its unique biologic behaviour, and challenges for clinicians in selecting therapeutic combinations offering maximum efficacy and minimum morbidity or long-term sequela currently under study in clinical trials....