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Endotypes in chronic rhinosinusitis: clinical relevance

Identifying endotypes enables personalised therapies that target specific pathophysiological processes, potentially resulting in better treatment outcomes for patients. The contemporary model of chronic rhinosinusitis (CRS) pathogenesis revolving around endotype, in combination with an expanding toolbox of diagnostics and therapeutics, enables...

OBITUARY: Lawrence Cleary 19/06/39 – 1/10/25

It is considerable sadness that we have to report the death of Lawrie Cleary. Lawrie Cleary played a major part in the history of cochlear implantation in the UK. He had lifelong hearing loss and was a patient of mine...

Human factors, theatre ethnographics and Girls Aloud

The issue of ambient music in the operating theatre is frequently controversial and has been known to cause ‘Bluetooth wars’, as different team members vie for control of the speakers. Our own Chris Potter gives his personal slant on this...

Plasticity with cochlear implants: individual factors in the outcomes

Andrej Kral gives us an overview of neuronal plasticity in congenital hearing loss, and discusses why it is core to our clinical interventions in hearing loss and rehabilitation. The brain is born immature and undergoes extensive shaping during early development....

Establishing a hearing service and ear hospital in Nepal: the Ear Aid Nepal experience

Following the earthquake that devastated Nepal in April 2015, the year ended on a positive note with the opening of an ENT hospital in Pokhara. Mike Smith, a UK-born ENT surgeon has been the driving force behind the conception and...

ENT and evidence-based medicine: How do they benefit each other?

How do we assess evidence, and how should ENT surgeons use EBM? Evidence-based medicine (EBM) is the practice of medicine based upon high quality scientific research. There are several formal definitions of EBM, the most widely quoted being that of...

The Oxford Textbook of Otolaryngology

JGG Ledingham was a famously affable man, the very epitome of the Oxford academic clinician with a legendarily unruffled bedside manner and razor-sharp intellect. He was awarded a personal Chair in Medicine in 1989 and such was his sangfroid, I...

The MACRO Trial: defining best management of chronic rhinosinusitis

A major UK trial in The Lancet finds ESS provides greater symptom relief than long-term macrolides for adults with CRS, supporting earlier surgery and fewer antibiotics. The MACRO Programme was established in 2016 when the UK National Institute of Health...

INTEGRATE: Uniting collaborative research in ENT

Exposure to clinical research as a trainee is often sporadic and unstructured, despite it featuring in both the GMC’s Good Medical Practice and the ISCP’s syllabus for all surgical specialities, including otolaryngology [1,2]. The majority of trainees undertake small-scale research...

Dysphagia in complex laryngology – maintaining the balance

These authors from the speech and language therapy department at Imperial College Healthcare NHS Trust, describe their view of a patient-centred approach to managing dysphagia in complex laryngology. Careful consideration of the balance of airway, voice and swallow, which is...

In conversation with De Wet Swanepoel, President of the International Society of Audiology

Gareth Smith caught up with the new President of the International Society of Audiology, De Wet Swanepoel, about the aims of the society, the upcoming World Congress of Audiology and the current state of hearing healthcare in Africa. De Wet...

The development of endoscopic sinus surgery – a meeting of three great minds

The story of the development of endoscopic sinus surgery is inextricably linked with the names of Stammberger, Messerklinger and Storz. Karl Storz’s daughter, Sybill Storz, tells us more. We would like to take this opportunity to express our appreciation of...