You searched for "genetic"

1614 results found

Harnessing head and neck cancer genomics for personalised medicine

Luc Morris updates us on the future of cancer diagnosis and treatment, which lies in “personalised oncology”, where specific molecular alterations of each tumour will be identified, and matched with actionable alterations in existing therapies, ushering in the era of...

Clinical Manual of Otolaryngology

This book aims to fill the gap that many ‘generic clinical textbooks’ fail to address; the knowledge and skills required to deal with common ear, nose and throat conditions that present to general practitioners and in emergency departments. Its scope...

Can writing reveal the timeline for future dementia diagnoses?

Frontotemporal dementia is the term for a group of dementias affecting behaviour and language. Thirty percent of FTD cases are associated with autosomal dominant mutations. There are three main genes that account for the majority of these genetic FTD cases...

The Royal College of Surgeons of Edinburgh: Foundations in Surgical Leadership June 26

The Royal College of Surgeons of Edinburgh Foundations in Surgical Leadership

The Royal College of Surgeons of Edinburgh: Foundations in Surgical Leadership April 26

Royal College of Surgeons Edinburgh Foundations in Surgical Leadership

Radiation-induced dysphagia in head and neck cancer

This is a helpful reference paper that provides an overview of the biomolecular effects of radiation on the tissues of the upper aero-digestive tract. The authors explain that radiation injuries occur in a repetitive and accruing manner over the duration...

Evolution of salivary gland pathology classifications

Targeted therapies for malignant salivary gland tumours have changed the treatment paradigm and therapy approaches. Better outcomes are now feasible. Choosing the treatment method requires a clear classification of the lesions. The authors of this paper reviewed the World Health...

On the influence of sex on tinnitus burden and its phenotypes

One important aspect of the new paradigm in tinnitus research is to question basic assumptions. What associations does the sex of a person have with their experience of and reaction to tinnitus? Chris Cederroth raises the question and tells us...

100,000 Genomes Project: in conversation with Tess Lopez

For Jul/Aug 2021, ENT & Audiology News features several contributions from the 100,000 Genomes Project, and Tess Lopez very kindly agreed to talk to me about her involvement with the project, as well as sharing her personal experiences of having...

The structure and function of DNA

DNA structure and replication Genetic information within multicellular organisms, including man, is stored in molecules of deoxyribonucleic acid (DNA), which reside within the chromosomes of each cell nucleus. A DNA molecule consists of two very long chains, or strands, of...

Nursing care for ENT patients

Increasingly within the UK, issues related to bed availability can lead to ENT patients receiving care away from previously well-established specialist wards. This is a cause for concern in many institutions and the authors looked to assess this. They demonstrated...

Bones, stones and surgical moans: rethinking PTH dynamics in parathyroid surgery

Intraoperative parathyroid hormone (IOPTH) testing has revolutionised minimally invasive unilateral parathyroidectomy (MIP) as the gold standard treatment for primary hyperparathyroidism, replacing old-timey four-gland exploration. IOPTH testing ensures reliable excision of all hypersecreting glands, including those pesky hard-to-find ones, without relying...