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Smoking and immunotherapy – does it worsen outcome?
This interesting study aimed to address the issue of smoking in patients who had their allergic rhinits treated by sublingual immunotherapy (SLIT). Assessment was with validated quality of life questionnaires. There were 163 patients recruited in Greece who had completed...
Risk factors for TORS treatment failure in HPV-related oropharyngeal cancers
HPV-related squamous cell cancers are an increasingly common cause of malignancy in the oropharynx. There is evidence that these cancers are associated with a significantly improved overall survival compared to conventional HPV-negative tumours. The optimal treatment for such cancers is...
No soup for you…! Early identification of postoperative perforation increases the success of conservative management
Iatrogenic perforation of the hypopharynx or cervical oesophagus is a well-recognised life-threatening complication. Previous studies have demonstrated that conservative management with broad-spectrum antibiotics and withholding oral feeding may avoid morbidity associated with surgical repair. This study addresses when conservative management...
T1 lip cancer and cervical lymph node metastases
The management of large lip squamous cell carcinoma (SCC) (T2, T3, T4 tumours) or those with nodal disease is well established. However the management of T1N0 tumours is controversial due to the assumed low risk of occult lymph node metastases....
Voice issues in transgender individuals
Recently, former decathlete and TV personality, Bruce Jenner, admitted that he is transgender, thereby becoming the most famous and vocal advocate for transgender issues. Transgender refers to female to male or male to female identification. In either case, voice modification...
Adjuvant intratympanic steroid therapy in sudden sensorineural hearing loss
Sudden sensorineural hearing loss (SNHL) means abrupt hearing loss by 30dB affecting three consecutive frequencies within 72 hours. This is treated by high tapering doses of systemic steroids, the role of which is controversial and fraught with possible complications in...
Semi dynamic reconstruction of the lower lip
The main goal of reconstructive surgery for facial paralysis is the restoration of smiling and function of eye closure. The deformity of the lower lip in paralysis is ptosis of the corner of the mouth, eversion of the vermillion and...
Multisystem pathology in refractory otitis media with effusion
Recurrent middle ear effusion is a common problem and so is rhinosinusitis with polyposis. It is not often thought that the problem could be linked to multisystem pathology, such as eosinophilic granulomatous with polyposis. Therefore, repeated grommet insertions and surgical...
Three years later: report on the state of well-being of patients with chronic tinnitus who underwent modified tinnitus retraining therapy
This paper reports on 130 patients with tinnitus of at least three months duration who underwent ‘Modified Tinnitus Retraining Therapy’ (MTRT). MTRT combines psychological and physical therapies with standard tinnitus retraining therapy provided as a course of multi-disciplinary treatment, as...
Military acoustic trauma: incidence and management
This is a retrospective study on the effects of acute acoustic trauma on the hearing thresholds of 225 military personnel. The main symptom after acute acoustic trauma due to firearm use was tinnitus. The authors consider it as the main...
New aminoglycosides with reduced ototoxicity risk
Aminoglycoside antibiotics are widely used for infections affecting patients of all ages and at different sites, however they carry a risk of ototoxicity, nephrotoxicity and rarely peripheral neuropathy. Preventing ototoxicity is crucial to the maintenance of auditory function and quality...
