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The effects of polypharmacy in the elderly
Another pill to cure the ill? Alec Lapira discusses the warning signs of polypharmacy in the elderly population. Polypharmacy in the elderly Polypharmacy – defined as the use of five or more medications – occurs in 20–37% of older people...APAM (Association of Physicians of Great Britain and Ireland) 118th Annual Meeting 2025
Welcome to APAM 2025 - What Awaits? APAM 2025, the 118th Annual Meeting of the AoPGBI, will take place on 3–4 April 2025 at the Royal College of Physicians in London. This prestigious event will bring together leading clinicians, researchers,...
The applicability and reliability of SHIMP, a new vestibular test, in adolescents
The video head impulse (now called the head impulse paradigm – HIMP) is now a routine test battery in neuro-otological practice. Few will be familiar with the new suppression head impulse paradigm (SHIMP) test. The key difference is that, in...Genetic research on hereditary hearing loss and clinical application in the Chinese population
Congenital deafness in China affects more people than the entire population of Australia. Prof Wang give us a comprehensive insight into one of the main congenital disabilities in China, looking into the causes of deafness and the benefits of genetic...
Canal plugging for intractable Meniere’s disease
In this single centre retrospective study, the authors applied semicircular canal plugging, well known as a treatment for refractory BPPV, to intractable unilateral Meniere’s disease (MD) that had failed to respond to medical treatment with betahistine and hydrochlorothiazide. However, in...The astronomer’s nose: Tycho Brahe’s controversial prosthesis
Tycho Brahe (1546-1601) is a familiar and colourful figure in the history of science. The immense quantity of data he collected during his lifetime would enable the work of Johannes Kepler and has gained him admission to the astronomical pantheon....Endolymphatic sac surgery: controversial procedure for the treatment of Ménière’s disease
Landmark Paper: Thomsen J, Bretlau P, Tos M, Johnsen NJ. Ménière’s disease: endolymphatic sac decompression compared with sham (placebo) decompression. Ann N Y Acad Sci 1981;374:820-30. Of all of the chapters in the Landmark Papers book, the chapter that discussed...Patient initiated follow-up in head and neck cancer
Is it time for a change in the way we follow up head and neck cancer patients after treatment? Paul Nankivell and Hisham Mehanna explain the rationale for the PETNECK2 trial. After completion of curative intent treatment, clinical follow-up currently...Targeting the microbiome in chronic rhinosinusitis
Researchers at St Paul’s Sinus Centre and UBC in Vancouver are testing a novel treatment for CRS: transferring mucus from a healthy donor into a patient’s sinuses. Chronic rhinosinusitis (CRS) is one of the most common diseases managed by otolaryngologists...Central auditory changes in SNHL
Robert Harrison discusses some of the most obvious ways in which cochlear hearing loss has central consequences. It is convenient to classify hearing loss according to the most obvious site of lesion, for example, conductive, cochlear, retro-cochlear, or central hearing...Vestibular dysfunction after cochlear implantation in children
Whilst vestibular dysfunction is a known outcome of cochlear implant surgery, do we know the risk factors associated with this, particularly in children? In this article a team from University of Tokyo discuss their findings. Cochlear implantation (CI) is an...
