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Dysplasia at the margins of laryngeal cancer specimens following laser resection – is conservative management appropriate?

Transoral laser microsurgery (TOLM) remains the cornerstone of treatment for early laryngeal squamous cell carcinomas. Whilst the hope is always to achieve a complete surgical excision with clear margins, it is sometimes the case that on histological analysis, disease is...

Office treatment for persistent rhinorrhoea

Vasomotor rhinitis (VR) is a common condition across the world. Patients suffering from VR commonly have symptoms of persistent bilateral rhinorrhoea, that can have a significant negative impact on their quality of life. Vasomotor rhinitis can be treated medically with...

What factors lead to poor outcomes for children with acute post-intubation laryngeal injuries?

Endotracheal intubation is well known to carry a risk of acute laryngeal injury. These problems range in severity and can lead to chronic problems but, when laryngeal injuries are identified and treated early, there are fewer complications. The authors of...

The hidden enemy of microtia reconstruction: cholesteatoma

Although ear reconstruction for concha-type microtia is generally successful, its frequent association with congenital aural stenosis introduces a hidden risk of cholesteatoma due to disruption of epithelial migration. This negatively affects hearing and reconstructive outcomes. This single-centre retrospective case series...

Adjuvant radiotherapy for locally advanced (T3–4) major salivary gland cancer – survival benefits quantified

Complete surgical excision of major salivary gland cancers (MSGCs) is the current mainstay of curative treatment for this disease. Indications for postoperative radiotherapy according to current UK national guidelines include high-grade tumours, advanced-stage (stage 3–4) tumours, involved resection margins, perineural...

A new tool to enhance smell recovery?

Vericiguat is a soluble guanylate cyclase activator which boosts intracellular cGMP and promotes smooth muscle relaxation. It is approved for use in heart failure, but the authors hypothesise that it may also enhance neuronal olfactory signalling via cGMP elevation. Eighty-eight...

Transoral coblation surgery – a viable option for early laryngeal cancers involving the anterior commissure?

Transoral laser microsurgery is widely considered to represent the ideal treatment modality for early (T1a) laryngeal cancers. With disease involving the anterior commissure however, radiotherapy is often advocated on account of perceived superior voice and airway outcomes, plus potential difficulty...