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Investigation of the role of KPNA2 biomarker in oral SCC invasiveness

This edition of Head and Neck has a strong focus on studies using immunohistochemistry (IHC) to elucidate potential roles of various cell-signalling molecules in both HNSCC and thyroid cancer. The ‘cellular-protein heavy’ title of this article may be off-putting to...

Alcohol consumption and the risk of developing benign laryngeal disorders?

Alcohol consumption among South Korean adults is apparently high, with over three quarters of the adult population consuming alcohol and a ‘high-risk’ drinking rate of one in five. Excessive alcohol consumption is considered to be a risk factor for developing...

Handbook of Otolaryngology, Head and Neck Surgery – Second Edition

The authors and contributors of this book have done a stellar job of updating the content while maintaining the portability essential for any ‘handbook’. They begin with a sound introductory section which presents a comprehensive road map to evaluating the...

In conversation with Professor David Kemp

Ted Killan, Vice-Chair of the British Society of Audiology (BSA), caught up with Professor Kemp to discuss his scientific journey over the past 40 years, and what we can expect from OAEs in the future. Prof David T Kemp. In...

Management of stage IV pharyngolaryngeal lesions

This is a retrospective study of 63 patients presenting with stage four laryngeal and/or hypopharyngeal squamous cell carcinoma. The aim was to define the factors influencing the oncological and functional outcomes of the patients. All patients had T4 lesions with...

Intermediate risk factors SCC tongue

This retrospective review from Japan assessed 89 patients who underwent surgery for squamous cell carcinoma of the tongue, specifically they reviewed the evidence of perineural and vascular invasion (27.0% and 23.6%). Their results suggest, not unsurprisingly, that perineural and vascular...

Free flap reconstruction in stage three bisphosphonate-related osteonecrosis

There is no widely accepted gold standard for the treatment of bisphosphonate-related osteonecrosis of the jaw (BRONJ). Early BRONJ is managed conservatively but there is controversy regarding the treatment of the later stages. Stage three is defined as exposed bone...

Assessing the impact of e-cigarette smoke on the vocal fold

While the use of electronic-cigarettes (e-cigs) is increasing rapidly, little is known about the effects this has on the health of vocal fold. In this translational research study, authors compared the effects of e-cig vapour and cigarette smoke on an...

Shooting for Gold: ENT surgery and the Commonwealth Games

What are the secrets to success in your career, sports and life in general? Sharp-shooter Parag Patel hits the bullseye again. I write this article following a wave of summer sporting brilliance, from the record Great Britain 67 medal haul...

MDT clinics for adults with learning disabilities and hearing loss

Healthcare providers can have limitations and challenges providing optimum care for patients with intellectual disabilities. Siobhan Brennan and Susanna Goodhart highlight key professionals and carers who may be instrumental when trying to deliver good management and care along with other...

Music and cochlear implants

Introduction The introduction of multichannel cochlear implants (CIs) in the early 1980s provided children and adults with severe and profound hearing losses with greatly improved speech perception skills. In this paper, however, I am going to focus on an area...

Database WG2. The Tinnitus Patient Database in the TINNET COST Action BM1306

Berthold Langguth describes an innovative project that is creating the world’s largest multi-national patient database containing standardised information on tinnitus and medical history, otological examination and psycho-acoustic measures of tinnitus. A challenge for tinnitus treatment and tinnitus research is the...