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COVID-19 in patients with chronic rhinosinusitis with polyps. Are they at risk?
COVID-19 entry factors are highly present in nasal epithelial cells. These factors include ACE2 and TMPRSS2. Their presence in patients with chronic rhinosinusitis with nasal polyps (CRSwNP) was not investigated before. Authors investigated expression of ACE2 and TMPRSS2 in two...
Molecular and genetic nature of skull base tumours drives management
This article reviews the molecular basis and paradigm shift in the diagnosis and management of skull base tumours. It is now known that the phenotype of meningiomas is influenced by their genotype. Endolymphatic sac tumours are observed in up to...
Is benign intracranial hypertension underdiagnosed in patients with spontaneous CSF leaks?
In ENT practice we come across spontaneous CSF leaks. Patients present either as unilateral watery rhinorrhoea or otorrhoea, or sometimes as hearing loss with a watery middle ear effusion. Clinicians, after confirming the diagnosis of CSF leak with beta 2...
The future of biologics?
This paper takes a deep dive into how eosinophilia affects the responsiveness of the host to the two monoclonal antibodies mepolizumab and bendralizumab, both of which are active against IL5. We know that eosinophils are attracted and trapped into the...
Motor learning: better knowing how, not how well
Motor learning is described as the ability to perform a motor skill due to practice and/or experience. Research on interventions to enhance limb motor skills can be influenced through the amount, distribution, variability and schedule of practice as well as...
Tympanometry with cochlear implants
Multifrequency and multicomponent tympanometry enables evaluation of minute changes in the middle ear system as well as changes in resonant frequency. Change in resonant frequency would indicate a change in the natural characteristics of the middle ear, such as mass...
Falls and ASL users
A mixed-method pilot study was carried out to assess the cognitive load of sign language among users and, consequently, the possible risk of injurious falls. The study specifically investigated the possible risk of falls due to the simultaneous activity of...The North of England Otolaryngology Society and the Midland Institute of Otolaryngology joint Spring Meeting
A nail-biting tiebreaker at the ENT-themed University Challenge. Haseem Raja, ST3 ENT Registrar, University Hospital Coventry & Warwickshire and Daniel Ahari, Academic Foundation Programme Year 1 Doctor at Manchester University NHS Foundation Trust. The North of England Otolaryngology Society and...3D printing and sustainability in audiology and ENT
As we try to avoid disposing of equipment that is still functional, we are challenged by company policies that make equipment ‘obsolete’ and no longer supported for repairs. One innovative solution is provided by 3D printing parts that are needed...Why and what should hearing care professionals know about cognitive impairment and dementia
Good reasons to care about cognitive impairment and dementia in audiology If asking people what they fear most when getting to old age, it is cognitive decline that is named most often. This comes with the expectation of limitations in...Mind the gap – developing a sustainable pipeline for hearing therapeutics
In this article, the authors describe three key challenges faced in developing hearing therapeutics. Collaboration between companies, sectors and disciplines will be key to finding solutions. The unmet need for therapies for hearing loss grows apace, with prevalence rising across...
