You searched for "technological"

1643 results found

Genetic discovery using animal models: presbyacusis

By their very nature, late-onset hereditary disorders offer a large window of opportunity for therapeutic intervention. However, before we can begin to think about strategies we need knowledge of the genetics and pathology underlying the condition. In this article we...

Hidden hearing loss in humans

Awareness of cochlear synaptopathy (‘hidden hearing loss’) is growing. Chris Plack gives us an introduction to the condition, defining it and reviewing recent research in humans and animals with respect to noise exposure. The main cause of hearing loss is...

To make a difference

Education and training have a key part to play in the development of leaders of the future; Dorte Hammershøi discusses the educational approaches taken in Denmark and the pros and cons of the methods used. Dorte also explains the BEAR...

Another use for Tisseel – plugging of the round window

After insertion of a cochlear implant electrode through the round window, there are several methods of sealing the perilymph leak and in my experience fascia (with varying amounts of attached muscle) seems to be most commonly used. Stephen O’Leary’s group...

Influence of smoking on vocal fold polyps

A vocal fold polyp is a benign lesion related to phonotrauma which induces upregulation of inflammatory processes and histological changes can occur in the epithelium and lamina propria. Whether smoking produces additional or enhanced changes is the subject of this...

Imaging and embolisation of paragangliomas

Paragangliomas are rare tumours within the head and neck and any article which succinctly jogs the memory with respect to their existence and subsequent accurate diagnosis is welcome. This article concisely explains the imaging techniques used to diagnose these tumours...

Synchronous bilateral tonsil cancer

There is a long-standing debate regarding either unilateral or bilateral tonsillectomy for histological confirmation of tonsil cancer. Bilateral tonsillectomy is the standard of care in Denmark for proven or suspected tonsil carcinoma, and in the diagnostic work-up of the unknown...

The effect on taste buds due to severing of the chorda tympani nerve

The long-term histological effect on taste buds following cutting of the chorda tympani in humans is not clear. Confocal laser scanning allows in-vivo examination of the same group of taste buds and is aiding our understanding of why patients recover...

Resection margins in head and neck surgery

Although an increasing proportion of head and neck malignancies are treated with non-surgical modalities, when surgery is undertaken an incomplete clearance results in significantly worse prognosis. However, the intraoperative assessment of an adequate margin is difficult. The personal practice of...

Facial paralysis risk factors in benign parotid surgery

The literature shows that the risk of facial paralysis following benign parotid surgery can be as high as 57% for temporary weakness and 7% for permanent facial nerve damage. It is generally thought that the factors involved may be related...

Chronic rhinitis endotypes

Chronic rhinitis (CR) is common with up to 30% of the population affected, with a significant impact on quality of life. CR includes several phenotypes with different pathogenesis including allergy, autoimmune, age, occupation, pregnancy, neurogenic and drugs. Such variation means...

A new treatment for septal perforations?

Nasal septal perorations are notoriously difficult to close surgically and can be extremely symptomatic and debilitating for the patient. This paper describes the use of carvacrol (a monoterpene phenol of the family Lamiacaea which is often found in essential oils)....