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Demonstrating unobservable effects of therapy through PROMS: a review
Ultimately, healthcare should meet the needs of the people it is designed for. One way of measuring this is using patient-reported outcome measures (PROMS). These tools capture the patient’s perspective and have been described as demonstrating the unobservable effects of...
eNOS and OME
The pathophysiology of otitis media with effusion (OME) is multifaceted. The authors tackled the nitrous oxide (NO) and platelet activating factor (PAF) pathways and the genetic polymorphism of endothelial nitrous oxide synthetase (eNOS). DNA analysis by PCR and restriction fragment...
Laryngeal oedema as a side-effect of tyrosine kinase inhibitor therapy
Tyrosine kinase inhibitors (TKIs) such as Imatinib are increasingly being used to treat haematological and solid malignancies. These agents have revolutionised the treatment of chronic myeloid leukaemia in particular. Although better tolerated than most conventional chemotherapy drugs, multiple side-effects have...
Risk factors for post laryngectomy fistula
This is a meta-analysis looking at the postoperative pharyngocutaneous fistula rates following total laryngectomy. The authors ended up with 34 studies with about 2500 patients. The most striking finding was that preoperative radiotherapy was a significant risk factor as well...
Which da Vinci surgical system? Novel flexible, single-port versus current multiport, rigid-arm robotic surgical system
The da Vinci robotic surgical system has transformed how oropharyngeal head and neck surgery can be delivered. The existing da Vinci Si model has challenges: the dimensions of this are larger than would be ideal for head and neck surgery...
Is non-allergic rhinitis as bad as allergic?
Non-allergic rhinitis (NAR) occurs when rhinitis symptoms are not associated with allergic, infective or anatomical reason. It is responsible for almost half of all cases of rhinitis and affects around 300 million worldwide. Assessing NAR patients’ quality of life (QoL)...
Tinnitus association with psychiatric and personality disorders
Tinnitus attracts large interest among researchers all over the world due to its negative psychological side-effects. This study aimed at investigating lifetime and current prevalence of psychiatric and personality disorders in patients with long-lasting and distressing tinnitus. Participants included 49...
Evidence for balloon eustachian tuboplasty
Balloon eustachian tuboplasty is an emerging intervention aimed at the management of eustachian tube dysfunction (ETD) and its sequelae. The authors acknowledge that ETD is a common but frequently ill-defined problem, with no well-established direct treatment. They performed a systematic...
Anatomic guidelines to endolymphatic sac in transmastoid approach – a cadaveric study
This study involved cadaveric dissection using transmastoid approach in cadaveric embalmed five half heads and posterior fossa approach in fourteen. The sac was identified by electron microscopy. The relatively consistent measurements were the relationship of the operculum to the internal...
Globus – benign when the sole symptom
This is a prospective cohort study of Danish patients that presented to an otolaryngologist’s office with globus over the course of a year. They accounted for 4% of new patients, amounting to 122 patients in this study (57 patients were...
Evaluation of secondary otalgia
This Turkish prospective study of 200 patients looked at the pain characteristics of secondary otalgia related to temporomandibular disorders (TMD) and cervical region disorders (CRD), and how they can affect diagnostics. Patients were included if they were >18 years of...
