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The structure and function of DNA
DNA structure and replication Genetic information within multicellular organisms, including man, is stored in molecules of deoxyribonucleic acid (DNA), which reside within the chromosomes of each cell nucleus. A DNA molecule consists of two very long chains, or strands, of...The future role of technology in rhinology
Technology is moving our speciality forward very rapidly in all domains, but none more so than in rhinology. David Whitehead looks at current and future trends. How will a surgeon justify their position in a team where artificial intelligence (AI)...OBITUARY: David Moffat (1948-2020)
David Moffat, one of the leading Otologists of his generation, died on 18 March in Addenbrooke’s Hospital in Cambridge, the hospital to which he had devoted his professional life. Having survived cancer of the prostate, he succumbed to a second...
Auditory neuropathy spectrum disorder
This is a concise summary of auditory neuropathy and current knowledge of the disorder through review of a recently published article. The terminology of this hearing disorder implies the site of the lesion is neural; however the characteristic electrophysical signature...
Smoking and immunotherapy – does it worsen outcome?
This interesting study aimed to address the issue of smoking in patients who had their allergic rhinits treated by sublingual immunotherapy (SLIT). Assessment was with validated quality of life questionnaires. There were 163 patients recruited in Greece who had completed...
Friendly bacteria in the ear nose and throat to combat the bad…
The author presents a thorough review of bacterial interference and the studies that have been conducted in common ENT conditions. The simple concept is that a strong population of normal flora will interfere with colonisation and subsequent infection by pathogenic...
Cheek reconstruction following melanoma excision
Malignant melanoma occurs most commonly on the cheek and thus is usually diagnosed early, and rarely needs large reconstructions for advanced disease. This is a retrospective study looking at 26 patients that had undergone treatment for cheek melanomas between 1996...
Tympanostomy tubes outcomes by tympanic quadrants- a meta-analysis
Tympanostomy tube (TT) insertion is one of the most common ENT procedures, resulting in millions of TTs being implanted per annum and occurring complications that need to be addressed. Premature TT extrusion (PTTE) is a well-recognised such complication, affecting almost...
Videofluoroscopic swallowing studies: balancing risks and benefits
Videofluoroscopic swallow studies (VFSS) are an important part of the diagnostic toolkit and arguably the current gold-standard for assessing swallow biomechanics and diagnosing dysphagia. However, the procedure does involve exposure to radiation, and any clinician requesting this should be able...
Parkinson’s humour: recognising social communication difficulties
Parkinson’s results in a progressive motor disease with symptoms including tremor, rigidity and bradykinesia. However, people with Parkinson’s also experience non-motor symptoms such as cognitive difficulties that can impact social communication, often due to their co-existing speech difficulties, auditory and...
