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Surviving oropharyngeal squamous cell carcinoma – does subsite matter?
Human papilloma virus (HPV) status is a known prognostic factor in oropharyngeal squamous cell carcinoma (OPSCC). The eighth edition of American Joint Cancer Committee (AJCC) has modified the TNM staging to reflect this. However, subsite as an independent prognostic factor...
Choline PET-CT: an accurate diagnostic tool for the detection of parathyroid adenoma?
Hyperparathyroidism (HPT) is an endocrine disorder characterised by an increase in the secretion of parathyroid hormone (PTH), with a resulting increase in calcium plasma levels, which can cause renal lithiasis, fractures, and osteoporosis, the most frequent symptoms of the disease....
SNOT-25 to assess CRS - a new tool
The SNOT-22 is a well-established validated instrument, designed to evaluate the rhinosinusitis-specific health status and health-related QOL, however makes only one broad reference to productivity. The objective of this paper is to evaluate a modified SNOT-25 created to better assess...
Endoscopic stapes surgery
This retrospective Turkish study looked at the audiological and surgical outcomes of 40 patients who underwent endoscopic stapes surgery over a three-year period. To assess the learning curve, the patients were divided into two groups based on the date of...
Does use of pectoralis muscle myocutaneous flap (PMMCF) reduce postoperative pharyngocutaneous fistula complication after salvage laryngectomy?
Salvage laryngectomy for recurrent laryngeal carcinoma following failed radiotherapy or chemoradiotherapy is associated with high postoperative complication rate. The primary aim of this paper was to assess whether use of muscle myocutaneous flap (PMMCF) as an interposition graft reduces the...
CI outcome measures and different languages
Outcome measures for hearing rehabilitation strategies in children are the subject of endless debate. The underlying problem with measuring outcomes in this population is delineating the extent to which development (which is in itself variable) and hearing ability (usually the...
Can we predict how much benefit patients will get from ESS with a novel monoclonal antibody
Mepolizumab (Nucala) is a humanised IgG1 monoclonal antibody that acts as an IL-5 antagonist. It has been shown to be highly effective in treating severe asthma. It is hypothesised that it will be effective for patients with recalcitrant CRSwNP. This...
Is there a limitation for excising parapharyngeal tumours transorally?
The parapharyngeal space is a complex anatomical space bounded medially by the oropharynx and laterally by the mandible. It is conceptualised as an inverted pyramid extending from base of skull above to the hyoid bone below. The space is divided...
Are there any benefits of postoperative antibiotics after endoscopic transsphenoidal surgery for pituitary tumours?
This prospective randomised double-blind multicentre study evaluated whether postoperative antibiotics resulted in improvement in sinonasal quality of life (QoL) compared to placebo in patients undergoing endoscopic endonasal transsphenoidal pituitary surgery. A total of 461 patients were screened for the study...
Assessment of audiological needs
A thorough assessment of audiological needs is crucial for a successful audiological rehabilitation. This study concentrated on creating the Québec Audiological Assessment Protocol for Younger and Older Adults (QAAP-YOA) that could be easily adopted in audiological clinics. The authors used...
Nothing about us without us: a how-to guide
Participatory design is an approach that is built around collaboration with users through a process of coproduction, design and creation. Most interventions are designed with the expert clinician researcher as the starting point, who looks at theory, evidence and their...
