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COOL therapy for cisplatin-induced hearing loss
Cisplatin is a commonly used cancer therapy, with nearly 50% of patients undergoing chemotherapy receiving cisplatin as part of their regimen [1]. Depending on the dose, incidence of hearing loss has been reported as 12-100% in adults, and 37-94% in...TEN testing in paediatric patients
Threshold equalising noise (TEN) testing is used to identify dead regions (DRs) of the cochlear. Alexandra Lusty considers the challenges of using the TEN test in the paediatric population as well as the importance of identifying DRs. Diagnosing dead regions...
Quality of life in children following balloon Eustachian tuboplasty
This study aimed to demonstrate the efficacy of balloon Eustachian tuboplasty (BET) in children by assessing their quality of life with the Otitis Media-6 questionnaire (OM-6). The OM-6 questionnaire is the most frequently used instrument to measure health-related quality of...
OTO-104 in noise-induced and cisplatin-induced hearing loss
These two animal studies report on potential new applications for intra-tympanic OTO-104, a slow-release hydrogel formulation of dexamethasone that is currently being used in a Europe-wide randomised trial for Ménière’s disease. In the first paper, guinea pigs were given a...
Seeking medical attention with tonsillectomy complications depends on who you are. Lessons from the USA
In the current UK model, NHS care is free at point of access so there are no perceived economic barriers to seeking attention with postoperative complications. This study from the US examines surgical and emergency room databases from across California,...
Oral hygiene and its interaction with standard of education on the risk of oral cancer in women
Oral cancer in women has an increasing incidence in China, although the majority of Chinese women don’t smoke or drink alcohol. Poor oral hygiene has been shown in previous studies to be a risk factor in the development of oral...Securing the future of ENT in the UK
A career in otolaryngology is fascinating, fulfilling and fun, but how do we convince our potential successors? Jay Doshi, Asad Qayyum, Bradley Storey and Tom Milner outline the fantastic efforts to showcase ENT throughout the UK. Student and foundation doctors...
Is combined two wall decompression approach a better surgical outcome for Grave’s orbitopathy?
This retrospective study looked at the outcome of endoscopic medial wall combined with transcutaneous lateral orbital wall decompression in Graves’ orbitopathy. The following parameters were studied: reduction in proptosis; change in visual acuity and diplopia. A total of 36 orbits...
Surgically improving pharyngeal paralysis and associated dysphagia
This was an interesting article explaining the current methods used to try and improve dysphagia and in some cases associated problematic aspiration following vagal injury. These patients are often those with other associated cranial neuropathies, with skull base lesions, brain...
Primary ossicular chain reconstruction in open-cavity mastoidectomy
The authors performed a retrospective analysis of 21 patients who had undergone primary reconstruction of the ossicular chain during canal-wall-down mastoidectomy. The ossiculoplasty technique used consisted of removal of the malleus head and division of tensor tympani, and rotation of...
Malignant craniopharyngiomas
Craniopharyngiomas are successfully managed with surgery and / or adjuvant chemoradiotherapy. The transnasal endoscopic route has become increasingly utilised in the management of these challenging tumours. This paper reviews 23 cases from the literature of the rarely reported malignant transformation....
