You searched for "antibiotics"
Zinc and rhinosinusitis
Patients with chronic rhinosinusitis (CRS) in general, and those with nasal polyps (CRSwNP) in particular, have been shown to have down-regulation of tight junction genes. Zinc, on the other hand, is well-known for its role in immune regulation and deficiency...
The future of biologics?
This paper takes a deep dive into how eosinophilia affects the responsiveness of the host to the two monoclonal antibodies mepolizumab and bendralizumab, both of which are active against IL5. We know that eosinophils are attracted and trapped into the...
Biopsy sites with a diagnosis of pemphigusand mucous membrane pemphigoid
This is a systemic review and met-analysis to critically evaluate optimal biopsy site for patients presenting with pemphigus or mucous membrane pemphigoid. Historically, diagnosis is made if H&E staining direct immunofluorescence and serological testing of auto-antibodies. Direct immunofluorescence has been...Jameel Muzaffar, Anne Schilder and James O’Hara
In a follow-up to the interview with Anne Schilder back in 2016*, Jameel Muzaffar speaks to Anne and to James O’Hara about the current research landscape in ENT in the UK. *Banerjee A. In conversation with Professor Anne Schilder. ENT...Jameel Muzaffar, Anne Schilder and James O’Hara
In a follow-up to the interview with Anne Schilder back in 2016*, Jameel Muzaffar speaks to Anne and to James O’Hara about the current research landscape in ENT in the UK. *Banerjee A. In conversation with Professor Anne Schilder. ENT...
Hydrogen peroxide and its uses in healthcare
This is an interesting review about the origin and uses of hydrogen peroxide, especially in neurosurgery. However, its uses are ubiquitous and applicable to several medical specialties. When hydrogen peroxide was first discovered in 1818 by Louis Thenard, it had...
Advances in diagnosis and management of allergic rhinitis
This article reviews advances in the diagnosis and management of allergic rhinitis. Recent advances in the diagnosis of allergic rhinitis include testing of local immunoglobulin E (IgE), urinary test to diagnose aspirin hypersensitivity and optical rhinometry to assess degree of...
A trial of house dust mite sublingual tablet in children with allergic rhinitis
The house dust mite (HDM) is one of the commonest causative agents in allergic rhinitis (AR), affecting patients across all demographics. Recently, sublingual immunotherapy (SLIT) has been shown in clinical trials and meta-analysis to be effective compared to placebo in...
Biologicals for severe chronic rhinosinusitis with nasal polyps. Any use?
Recent advances and knowledge of inflammatory endotypes of chronic rhinosinusitis with nasal polyps (CRSwNP) led to introduction of biological agents such as monoclonal antibodies targeting IgE (omalizumab) and Interleukins (ILs) such as IL4R alpha (dupilumab) and IL5. The European Academy...
