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The stubborn polyp cases are ‘different’

The widely different behaviour of nasal polyp disease between patients is a major feature of rhinology practice and makes counselling of patients difficult when approaching their first operative intervention. Setting aside aspirin sensitivity (Samter’s triad), which is known to be...

Zinc and rhinosinusitis

Patients with chronic rhinosinusitis (CRS) in general, and those with nasal polyps (CRSwNP) in particular, have been shown to have down-regulation of tight junction genes. Zinc, on the other hand, is well-known for its role in immune regulation and deficiency...

The future of biologics?

This paper takes a deep dive into how eosinophilia affects the responsiveness of the host to the two monoclonal antibodies mepolizumab and bendralizumab, both of which are active against IL5. We know that eosinophils are attracted and trapped into the...

Biopsy sites with a diagnosis of pemphigusand mucous membrane pemphigoid

This is a systemic review and met-analysis to critically evaluate optimal biopsy site for patients presenting with pemphigus or mucous membrane pemphigoid. Historically, diagnosis is made if H&E staining direct immunofluorescence and serological testing of auto-antibodies. Direct immunofluorescence has been...

Jameel Muzaffar, Anne Schilder and James O’Hara

In a follow-up to the interview with Anne Schilder back in 2016*, Jameel Muzaffar speaks to Anne and to James O’Hara about the current research landscape in ENT in the UK. *Banerjee A. In conversation with Professor Anne Schilder. ENT...

Jameel Muzaffar, Anne Schilder and James O’Hara

In a follow-up to the interview with Anne Schilder back in 2016*, Jameel Muzaffar speaks to Anne and to James O’Hara about the current research landscape in ENT in the UK. *Banerjee A. In conversation with Professor Anne Schilder. ENT...

Hydrogen peroxide and its uses in healthcare

This is an interesting review about the origin and uses of hydrogen peroxide, especially in neurosurgery. However, its uses are ubiquitous and applicable to several medical specialties. When hydrogen peroxide was first discovered in 1818 by Louis Thenard, it had...

2020 Unmasked: Hidden strengths and vulnerabilities laid bare - By Joseph Sinnott

Masks were everywhere in 2020. The most visible to stop the spread of COVID-19 but others concealed soon-to-be revealed strengths and weaknesses. In April 2020, the UK Prime Minister was taken to intensive care suffering with this new and frightening...

Globe Trotting and 62 years of ENT

Vasant Oswal was, for many years, ‘Mister ENT’ in the Northeast of England. Appointed as a consultant to the old North Riding Infirmary in 1970, he led what was a small and little-known department through a period of tumultuous change...

ENT leadership

Challenges The first challenge is to agree what we mean by the term leadership because there are many different ways in which the term is used. What is, however, a consensus is that the key distinction between leadership and management...

Andreas Wagner: ESPO 2025 keynote speaker

The keynote speaker for ESPO 2025 in Stuttgart is renowned evolutionary biologist and author Professor Andreas Wagner, from Zurich. Prof Wagner will focus on the congress theme of ‘Innovation’, giving us his unique perspective on how evolution drives human creativity....

Andreas Wagner: ESPO 2025 keynote speaker

The keynote speaker for ESPO 2025 in Stuttgart is renowned evolutionary biologist and author Professor Andreas Wagner, from Zurich. Prof Wagner will focus on the congress theme of ‘Innovation’, giving us his unique perspective on how evolution drives human creativity....