You searched for "antibiotics"

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Biopsy sites with a diagnosis of pemphigusand mucous membrane pemphigoid

This is a systemic review and met-analysis to critically evaluate optimal biopsy site for patients presenting with pemphigus or mucous membrane pemphigoid. Historically, diagnosis is made if H&E staining direct immunofluorescence and serological testing of auto-antibodies. Direct immunofluorescence has been...

Acupuncture for tonsillectomy pain in children

The challenge: tonsillectomy pain Tonsillectomy is a uniform surgical insult which results in a 10-day recovery for children. Severe pain can occur which can give rise to poor oral fluid intake, dehydration and potentially the need for intravenous fluid resuscitation....

Jameel Muzaffar, Anne Schilder and James O’Hara

In a follow-up to the interview with Anne Schilder back in 2016*, Jameel Muzaffar speaks to Anne and to James O’Hara about the current research landscape in ENT in the UK. *Banerjee A. In conversation with Professor Anne Schilder. ENT...

Jameel Muzaffar, Anne Schilder and James O’Hara

In a follow-up to the interview with Anne Schilder back in 2016*, Jameel Muzaffar speaks to Anne and to James O’Hara about the current research landscape in ENT in the UK. *Banerjee A. In conversation with Professor Anne Schilder. ENT...

Hydrogen peroxide and its uses in healthcare

This is an interesting review about the origin and uses of hydrogen peroxide, especially in neurosurgery. However, its uses are ubiquitous and applicable to several medical specialties. When hydrogen peroxide was first discovered in 1818 by Louis Thenard, it had...

Advances in diagnosis and management of allergic rhinitis

This article reviews advances in the diagnosis and management of allergic rhinitis. Recent advances in the diagnosis of allergic rhinitis include testing of local immunoglobulin E (IgE), urinary test to diagnose aspirin hypersensitivity and optical rhinometry to assess degree of...

A trial of house dust mite sublingual tablet in children with allergic rhinitis

The house dust mite (HDM) is one of the commonest causative agents in allergic rhinitis (AR), affecting patients across all demographics. Recently, sublingual immunotherapy (SLIT) has been shown in clinical trials and meta-analysis to be effective compared to placebo in...

Biologicals for severe chronic rhinosinusitis with nasal polyps. Any use?

Recent advances and knowledge of inflammatory endotypes of chronic rhinosinusitis with nasal polyps (CRSwNP) led to introduction of biological agents such as monoclonal antibodies targeting IgE (omalizumab) and Interleukins (ILs) such as IL4R alpha (dupilumab) and IL5. The European Academy...

Immunosuppresants and ototoxicity

There is a wide range of immunosuppressant drugs ranging from calcineurin inhibitors (e.g. cyclosporine), anti-folic agents (e.g. methotrexate) to anti-TNF and monoclonal antibodies, many of which could be ototoxic. The authors performed a systematic review assessing ototoxicity secondary to immunosuppressant...

Thyroid dysfunction and Meniere’s disease: is there a relationship?

The set of symptoms described as Meniere’s disease may have several causative factors. Timothy Hain and Patthida Maroongroge look for a relationship in the literature between Meniere’s disease and hypothyroidism. Meniere’s disease (MD) affects around two in 1000 people and...

2020 Unmasked: Hidden strengths and vulnerabilities laid bare - By Joseph Sinnott

Masks were everywhere in 2020. The most visible to stop the spread of COVID-19 but others concealed soon-to-be revealed strengths and weaknesses. In April 2020, the UK Prime Minister was taken to intensive care suffering with this new and frightening...

Globe Trotting and 62 years of ENT

Vasant Oswal was, for many years, ‘Mister ENT’ in the Northeast of England. Appointed as a consultant to the old North Riding Infirmary in 1970, he led what was a small and little-known department through a period of tumultuous change...