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Harnessing head and neck cancer genomics for personalised medicine

Luc Morris updates us on the future of cancer diagnosis and treatment, which lies in “personalised oncology”, where specific molecular alterations of each tumour will be identified, and matched with actionable alterations in existing therapies, ushering in the era of...

Endoscopic ear surgery in children

The benefits of endoscopes in otologic surgery, which have become increasingly widely appreciated in recent years, are very well suited to the management of paediatric middle ear disease. Although one might imagine that the smaller ear canal of a child...

10 steps to improving transition to adult services

Children and parents like the reassurance that staying under the care of the team who looked after them from birth gives, but as the child approaches adulthood he / she must come under the care of a new team. This...

Intraoperative nerve monitoring: 2017

Having written the definitive text on laryngeal nerves, Gregory Randolph and Dipti Kamani describe the benefits of intraoperative neural monitoring and, importantly, how to proceed if the nerve is pathologically involved or there is loss of signal. Over the years,...

Using tele-audiology in Zambia’s ear and hearing care desert

Addressing the medical desert with tele-audiology and tele-education. If a ‘medical desert’ is defined as a community that lives more than 60 miles away from the nearest acute care hospital, then try to imagine an appropriate term for a situation...

Differing outcomes of three Sub-Saharan Africa journeys with the common goal of task sharing in audiology

Task sharing can be designed and implemented specific to the needs of each programme. Foundational principles of global health include developing local leadership as a means to successful sustainable service provision in low- and middle-income countries (LMIC) or regions. It...

Supporting music listening through cochlear implant services – experience from a UK adult clinic on supporting musical engagement

The perception and enjoyment of music is central to many people’s lives. Harriet Crook (herself a cochlear implant recipient) tells us about important work in this area for people using hearing aids and CIs. There is now a wealth of...

Reducing hierarchy for individuals and teams across ENT

Alexander Pope said that “to err is human”, but medical errors can have serious consequences. How can better communication minimise the risk of them occurring in the first place? Allowing all members of the surgical team to feel empowered to...

Intratympanic steroids in Ménière's disease: what’s the evidence?

The days of drastic surgery for Ménière's disease are long gone. We know that intratympanic injections can deliver high doses of medication to the inner ear with minimal discomfort and minimal risk. But how do we choose from the myriad...

Old age is hard to swallow

This article takes us through the diagnosis and management of swallowing problems common in older age. As our global population continues to grow and live longer, dysphagia will continue to be a global problem which needs to be recognised, understood...

Endotypes in chronic rhinosinusitis: clinical relevance

Identifying endotypes enables personalised therapies that target specific pathophysiological processes, potentially resulting in better treatment outcomes for patients. The contemporary model of chronic rhinosinusitis (CRS) pathogenesis revolving around endotype, in combination with an expanding toolbox of diagnostics and therapeutics, enables...

The challenges in the risk stratification of thyroid nodules and cancers: the role of molecular testing

Around the world, molecular testing is becoming more widely used to personalise the management of thyroid nodules. Thyroid nodules are relatively common. They are palpable in ~5% of the population, while high-resolution ultrasound (US) incidentally finds them in 19–68% of...