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The Journal of International Advanced Otology cover image.

Immunosuppresants and ototoxicity

5 July 2022 | | Otology
There is a wide range of immunosuppressant drugs ranging from calcineurin inhibitors (e.g. cyclosporine), anti-folic agents (e.g. methotrexate) to anti-TNF and monoclonal antibodies, many of which could be ototoxic. The authors performed a systematic review assessing ototoxicity secondary to immunosuppressant...

Thyroid dysfunction and Meniere’s disease: is there a relationship?

1 July 2017 | | Audiology - Adult, Audiology - Diagnostic, Audiology - Paediatric, Vestibular Disorders
The set of symptoms described as Meniere’s disease may have several causative factors. Timothy Hain and Patthida Maroongroge look for a relationship in the literature between Meniere’s disease and hypothyroidism. Meniere’s disease (MD) affects around two in 1000 people and...

A trial of house dust mite sublingual tablet in children with allergic rhinitis

1 May 2019 | | Audiology - Adult, Auditory Implants, Neurotology, Otology, Tinnitus, Vestibular Disorders | SIT, SLIT, allergens, inhalative allergens, rhinitis, allergic, clinical trials, specific immunotherapy
The house dust mite (HDM) is one of the commonest causative agents in allergic rhinitis (AR), affecting patients across all demographics. Recently, sublingual immunotherapy (SLIT) has been shown in clinical trials and meta-analysis to be effective compared to placebo in...

Advances in diagnosis and management of allergic rhinitis

1 May 2018 | | Allergen immunotherapy, Allergic rhinitis, Aspirin-exacerbated respiratory disease, Immunoglobulin E
This article reviews advances in the diagnosis and management of allergic rhinitis. Recent advances in the diagnosis of allergic rhinitis include testing of local immunoglobulin E (IgE), urinary test to diagnose aspirin hypersensitivity and optical rhinometry to assess degree of...

Chronic rhinosinusitis management: back to the future?

1 July 2016 | | ENT, Rhinology / Sinus
Immunology is a dim and distant medical school memory to many ENT surgeons, but the increasingly complex immunology of chronic rhinosinusitis is fascinating (honestly!). Medical management options in CRS no longer just involves saline and steroids, and we need to...

In conversation with Prof Metin Önerci

30 April 2020 | | ENT, Rhinology / Sinus
Prof Valerie Lund caught up with friend and colleague, Prof Dr Metin Önerci, to discuss his various positions in rhinology, the FOAM programme with which he is involved, and rhinology in Turkey and the Balkan and the Central Asian region....

The search for pharmacological treatments for hearing loss and tinnitus

1 November 2016 | | Audiology - Adult
Where are we in our search for a hearing restoration grail? Nicola Robas leads us through the map pieces discovered in creating a pharmaceutical answer to hearing loss and tinnitus. Together, hearing loss and tinnitus affect over one in six...

In conversation with Miss Romola Dunsmore “ENT training in my day”

1 September 2015 | | ENT
Emma Stapleton is an ST8 in Otolaryngology at Doncaster Royal Infirmary, UK. For her first Trainee Matters article, Emma and her colleague, Ruth Capper (Department of Otolaryngology Head and Neck Surgery, Doncaster Royal Infirmary), spoke to 92-year-old ENT surgeon Romola...

Partial reconstruction of the pinna

1 September 2016 | | Otology
Reconstruction of the pinna is one of the most challenging procedures in facial plastic surgery. Although there has been significant progress since one of the earliest recorded descriptions by Sushruta in 600 BC, the complex three-dimensional structure of the pinna...

Human immunodeficiency virus and hearing impairment

1 July 2017 | | Audiology - Adult, Audiology - Diagnostic, Audiology - Paediatric, Otology
With an estimated 36.7 million individuals living with HIV / AIDS and literature reporting that these conditions contribute to hearing loss, it is surprising that more focus and resources are not employed to tackle this major hearing health concern. Yolandé...

Lies, damned lies and relative risk reduction

4 September 2023 | | ENT
Chris Potter has a thing or two to say about the use of statistics and, in doing so, he takes us to a Friday night steak house that is prone to airway disasters and on a short tour of his...

Implants and the identity of self

4 September 2023 | Audiology - Adult, Auditory Implants
Hearpeers is MED-EL’s international community for people with hearing implants and those considering getting a hearing implant, as well as their families and friends. This group enables people to connect with hearing implant recipients from around the world to learn...