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Endotypes in chronic rhinosinusitis: clinical relevance

Identifying endotypes enables personalised therapies that target specific pathophysiological processes, potentially resulting in better treatment outcomes for patients. The contemporary model of chronic rhinosinusitis (CRS) pathogenesis revolving around endotype, in combination with an expanding toolbox of diagnostics and therapeutics, enables...

Rapid genetic testing to avoid hearing loss in neonates

Thousands of newborn babies could avoid a lifetime of hearing loss thanks to a new rapid genetic test. In this article, we learn how. We have demonstrated for the first time that a rapid genetic test from a cheek swab...

Murder most foul, strange and unnatural

Hamlet, written by William Shakespeare at the very beginning of the 17th century has definite otological interest. The whole play is about young Prince Hamlet’s revenge for his father’s murder. The king is killed by Hamlet’s wicked uncle, who then...

History of ENT - Murder most foul, strange and unnatural

Hamlet written by William Shakespeare at the very beginning of the 17th century has definite otological interest. The whole play is about young Prince Hamlet’s revenge for his father’s murder. The king is killed by Hamlet’s wicked uncle, who then...

Imaging in hyperparathyroidism

Following their caudal migration at eight weeks of development, the parathyroid glands normally locate posterolaterally to the upper pole of the thyroid gland at the level of the cricoid cartilage (superior parathyroid glands arising from the fourth branchial pouch and...

A surgeon’s perspective on the challenges facing cochlear implantation in children

Cochlear implantation in children offers a different set of challenges and goals to adult practice. In this article, Iain Bruce, Professor of Paediatric Otolaryngology in Manchester, UK, explains some of the current clinical and research challenges in paediatric cochlear implantation,...

Anaesthesia for excision of vestibular schwannomas

The ‘shared airway’ relationship between ENT surgeons and anaesthetists is well documented. But ENT surgery and anaesthesia interact in numerous other ways, particularly in complex skull base surgery. What do our anaesthetic colleagues want us to know about vestibular schwannoma...

The future of hearing care and the role of audiology

The Clinical Director of Cincinnati Children’s Hospital Medical Center and President-elect of the American Academy of Audiology reviews the status of the present day audiologist’s remit, and discusses the changes we can expect with the changing demographic and behaviour of...

A multidisciplinary approach to the management of the adult balance - dizzy patient

Richard Gans and Kimberly Rutherford, renowned experts from The American Institute of Balance, give their team’s overview of the stages involved in reaching ‘diagnosis based strategies’. For the dizzy patient, this focuses on patient-centred clinical pathways for individualised therapy with...

Microgravity: an extreme environment for otolith organs

Motion sickness in a car can be upsetting for all involved. Transferring this concept into a tiny cabin bound for space could have devastating consequences. Are the processes involved in ‘space motion sickness’ the same as motion sickness? How do...

Lies, damned lies and relative risk reduction

Chris Potter has a thing or two to say about the use of statistics and, in doing so, he takes us to a Friday night steak house that is prone to airway disasters and on a short tour of his...

Hyposalivation: a review of current and future treatments

Hyposalivation remains a stubbornly difficult condition to treat, but novel therapies may not be far away. Saliva has many essential functions, including aiding digestion and swallowing, lubrication, maintaining tooth integrity and antibacterial activity. When patients experience reduced saliva production (hyposalivation),...