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A novel graft material for endoscopic tympanoplasty using the pre-tragal SMAS layer
The traditional biological graft materials for providing a scaffold for tympanic membrane reconstruction include temporalis fascia as well as conchal and tragal perichondrium/cartilage. This group from Taiwan present a novel graft option using the superficial musculo-aponeurotic system (SMAS) layer. They...
A single blinded RCT comparing triamcinolone with 5-FU treatment for keloid scars
This single blinded RCT compared 43 patients with 50 symptomatic keloids that were randomised to two matched groups of 25 scars, receiving either 5-fluorouracil (5-FU) or current first line treatment, triamcinolone (TAC). The surgeon administering the injectable treatments was unblinded,...Targeting the microbiome in chronic rhinosinusitis
Researchers at St Paul’s Sinus Centre and UBC in Vancouver are testing a novel treatment for CRS: transferring mucus from a healthy donor into a patient’s sinuses. Chronic rhinosinusitis (CRS) is one of the most common diseases managed by otolaryngologists...Systemic agents in thyroid cancer
For those patients who have disseminated or unresectable thyroid cancer, Dr Arabella Hunt and Dr Kate Newbold review systemic treatments, their differences, toxicities and outcomes. Thyroid cancer is the most common endocrine malignancy. It is subdivided into differentiated (papillary, follicular...What’s new in protecting hearing?
Preventing an avoidable hearing loss before it begins would be the public health dream. In this article Kathleen Campbell takes us through one option that is showing the potential to fulfil that ambition. Kathleen explains the development of a preventative...Cochlear implant referral: how can we do better?
Considerable progress has been made over the last few years in improving access to cochlear implantation (CI) in the UK for children and adults with severe to profound deafness. But we are still not treating children early enough, and we...
Is a hemithyroidectomy as effective as a total thyroidectomy for compressive symptoms?
The claim made in the title of this paper, that hemithyroidectomy is equally as successful as total thyroidectomy in alleviating compressive symptoms from goitres, is certainly intriguing. And with the inclusion of 45,539 subjects, it would at first glance seem...
Bell’s palsy – antivirals and steroids for all?
The role of antiviral medications in the treatment of Bell’s palsy remains somewhat controversial. Antivirals alone do not appear to be helpful, whereas numerous studies have shown that corticosteroids improve the chance of a full recovery compared to placebo. What...
Tranexamic acid and blood loss in bimaxillary surgery
This is a randomised double-blind placebo-controlled trial from Thailand to clarify the most effective dose of Tranexamic acid in reducing blood loss during a bimaxillary osteotomy. They confirmed that the dose of 10mg per kg is the most efficacious and...The changing landscape for hearing loss therapeutics: novel advances of gene and cell therapies
Recent years have seen advances in hearing loss therapeutics, with novel treatments trialled in humans, and others nearing promising first-in-kind clinical trials. First successful clinical trials for a specific form of genetic hearing loss Very exciting news has emerged in...
Live versus e-learning – which is the most effective communication training approach for health care staff?
If staff are unable to communicate with their patients this can impact negatively on the patient’s healthcare. They may be excluded from decisions about their own care and their rights to informed consent may be violated. Conversation partner training has...
