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Biologics for deafness
Cochlear implants and hearing aids are inherently limited in their ability to restore ‘natural’ hearing. Biological therapy to treat inner ear pathology still is evolving rapidly with several ongoing clinical trials, though none are available for clinical practice to date....
Case study suggesting mtDNA mutation as a tinnitus factor: ND1:m.3394T>C
Konadath et al report a genetic case study of a 24-year-old female experiencing reduced hearing sensitivity and tinnitus along with a blocked sensation in her right ear, sudden onset one year prior with no other otological complaints. Standard audiometry along...
Occupational dust exposure and nasal polyposis
This interesting European cross-sectional study demonstrates a link between occupational dust exposure and the presence of nasal polyposis. A random sample of textile workers (215) and retail store employees (101) in Portugal was taken, with clinical data gathered through a...Long-term outcomes of children and young people with cochlear implants
Introduction Profound childhood hearing loss has a huge impact on early communication skills, the acquisition of spoken language, and hence on educational attainments and employment prospects. Over the centuries, educators of the deaf attempted to overcome the challenge by using...
A comparison between artificial and cadaveric temporal bones in terms of providing realistic setting and structural details
Increasing difficulties, costs and risks of infection have led to the use of artificial temporal bones for training in mastoid and middle ear surgery. Whether these provide a realistic learning environment (face value) and offer structural details to learn from...COVID-19: UCT-Africa Virtual ENT transcends academic silos
The COVID-19 pandemic has been a global catastrophe with far-reaching consequences felt across many fronts around the world. One such aspect is the training of the future generation of ENT surgeons. With routine elective activity curtailed, academic conferences cancelled, and...On the shoulders of giants: a reflection on Wolfgang Steiner
Professor Wolfgang Steiner. Wolfgang Steiner inspired a whole generation of head and neck surgeons. Terry Jones gives us his own personal perspective. “We are like dwarfs on the shoulders of giants, so that we can see more than they, and...Vicarious (nasal) menstruation
Hippocrates himself is known to have said that when a woman’s menses are due, but instead of the usual vaginal menstrual flow, she has a haemorrhage from the nose, then this is a sure sign of pregnancy [1]. Artist’s impression...
Vestibular functions of hereditary hearing loss patients with GJB2 mutations
Mutations of the GJB2 gene are a common cause of deafness, being found in 15-25% of cases of congenital deafness. Over 100 mutations are now recognised and may be associated with a hearing loss ranging from mild to profound. This...
A higher aspiration for fine needles
Fine needle aspiration biopsy (FNAB) has aided in the diagnosis and management of thyroid nodules for decades. Now a rapid evolution is hoped to benefit an increasing cohort of patients with small nodules and non-diagnostic investigations. This review discusses the...
Those little friends in our noses
Human microbiota plays an important role in both health and disease including metabolism, immunomodulation, and a potential role in chronic inflammatory conditions such as chronic rhinosinusitis (CRS). The authors aimed to investigate the sinonasal microbiome using 16S rRNA gene sequencing...
