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Closing the circle: where art, science and humanity meet

As the final cover of this Art meets Science series arrives in your hands, I find myself filled with gratitude. Gratitude for the journey, for the people who walked it with me and, above all, for the deeper purpose that...

The future of inner ear drug delivery

The techniques for delivering drugs to the inner ear system are evolving. Jeffrey Harris considers the myths, the facts and the potential for drug delivery innovations and how they can improve tomorrow’s hearing outcomes. The inner ear’s delicate membranous structure,...

Intraoperative nerve monitoring: 2017

Having written the definitive text on laryngeal nerves, Gregory Randolph and Dipti Kamani describe the benefits of intraoperative neural monitoring and, importantly, how to proceed if the nerve is pathologically involved or there is loss of signal. Over the years,...

Surgical challenges in advanced or recurrent thyroid malignancy

The management of thyroid malignancy and extent of surgery is controversial, especially considering the limitations of preoperative diagnosis. Neil Tolley provides guidance and reminds us of our responsibility not to over-treat. In the UK, 16% of thyroidectomies are performed for...

The structure and function of DNA

DNA structure and replication Genetic information within multicellular organisms, including man, is stored in molecules of deoxyribonucleic acid (DNA), which reside within the chromosomes of each cell nucleus. A DNA molecule consists of two very long chains, or strands, of...

Giacomo Puccini’s laryngeal cancer

Giacomo Puccini, one of the best known composers of all time, was diagnosed with laryngeal cancer and died from the disease in 1924. In this article, Rosario Marchese-Ragona and Alessandro Martini describe Puccini’s experience of the disease with quotes from...

International Federation of Head and Neck Oncologic Societies (IFHNOS): its programmes and impact on head and neck cancer worldwide

In the first article of this edition, we introduce IFHNOS, which has created a major impact on the landscape of head and neck cancer treatment and education over the past quarter of a century by offering a global platform amongst...

Recalcitrant chronic rhinosinusitis: What to do next?

Whilst the majority of patients with chronic rhinosinusitis (CRS) will significantly improve with treatment, we are sometimes left with a ‘hard-core’ of nasal cripples who fail to improve despite our best efforts. How can we deal with these patients? Valerie...

Type 1 thyroplasty using a novel and inflatable implant from APrevent® VOIS

Unilateral vocal cord immobility severely impacts voice, swallowing, and airway functions. A novel approach offers adjustable medialisation for improved patient outcomes. Unilateral vocal cord immobility (UVCI) can cause significant disability to voice, swallowing, and airway functions. Patients with UVCI may...

Rotational chair testing: “To rotate, or not to rotate, that is the real question”

Passive whole body rotation tests are widely considered to be the ‘gold standard’ for the identification of bilateral peripheral vestibular disorders (bPVD), but also have a part to play in identifying unilateral disorders (uPVD). In this article Paul Radomskij discusses...

Balloon dilatation of the eustachian tube - largely very safe but not entirely without risk

Consent is a fundamental part of our daily working lives. This is something as simple as consent to examine a patient, consent to undertake a procedure as minor as taking blood, through to consent for a major operation. Whatever the...

Temperature-controlled radiofrequency treatment of the nasal valve confers sustained benefit

Aiming to investigate long-term efficacy and safety (three years post treatment), this was an extension of a previous multicentre, prospective, single-blinded, randomised controlled trial that investigated the effectiveness and safety of temperature-controlled radiofrequency treatment (TCRF) to the nasal valve (NV)...