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Can we predict how much benefit patients will get from ESS with a novel monoclonal antibody
Mepolizumab (Nucala) is a humanised IgG1 monoclonal antibody that acts as an IL-5 antagonist. It has been shown to be highly effective in treating severe asthma. It is hypothesised that it will be effective for patients with recalcitrant CRSwNP. This...
Coblation for lingual haemangiomas
Haemangiomas are benign vascular tumours characterised histologically by a marked proliferation of blood vessels. They can be either congenital or acquired, and can affect the tongue, both within the oral cavity and the oropharynx. A variety of interventions exist for...
Olfactory and gustatory recovery in coronavirus patients after six months
It remains unclear for how long olfactory and gustatory losses persevere in patients with COVID-19. This is a prospective study of 300 patients who lost taste and smell within seven days of contracting COVID-19. The patients were objectively assessed with...
All you need to know about childhood hearing loss - an update
This is an excellent update on childhood hearing loss. It is a comprehensive collection of five chapters, providing a summary of a broad range of practice guidelines to inform screening, diagnosis, and management of hearing loss in children. It has...
Indication and timing of electrodiagnostic tests in facial palsy
This excellent review describes the benefits and limitations of electrodiagnostic testing for patients with facial paralysis. Tests such as Schirmer, stapedial reflex and electrogustometry have been largely replaced by neurophysiologic tests like nerve excitability test (NET), electroneuronography (ENoG), surface electromyography...
Postoperative bleeding rates after inferior turbinate reduction using three different techniques
The most serious complication of inferior turbinate reduction surgery is postoperative bleeding, soon after the operation or later on. In this study comprising 751 patients, the authors have compared three common methods. Partial turbinectomy involved resection of the inferior turbinate,...
Endolymphatic sac tumours
The authors performed a systematic review of literature and describe the clinical signs and symptoms of endolymphatic sac tumours (ELST) in this article. A total of 113 patients and 118 cases from 26 studies were included in the study. The...
A new treatment for chronic rhinitis
The review paper looks at the efficacy of cryoablation of the posterior nasal nerve (PNN) to treat chronic rhinitis, an increasingly popular method of treating a highly prevalent and morbidity-inducing disease. Five studies were included in the meta-analysis, all dating...
Long-term results for dupilumab are very promising!
Eosinophilic chronic rhinosinusitis (eCRS) is complicated by frequent early and aggressive recurrence of polyps after both medical and surgical treatment regimes. Dupilumab is an anti-IL-4/IL-3 receptor monoclonal antibody and has been previously studied in the SINUS-52 study, with an observation...
Vestibular schwannoma surgery and inner ear injuries
Iatrogenic inner ear injury during vestibular schwannoma (VS) surgery ranges between 20% and 30% in the literature. However, there is no up-to-date quantification of such injuries, hence this study. The authors conducted a US-multicentre database search looking for patients who...
