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Celebrating deaf identity through art: the ‘Hearing Care for ALL’ Virtual Gallery Project
Dr Dalia Tsimpida tells us about the art initiative she created in the midst of the pandemic to promote ear and hearing care, and celebrate the vibrant and diverse world of deaf identity. In the face of the COVID-19 pandemic,...Why does music move us? Music as auditory signals of emotion
Music forms an integral part of the lives of people in all known cultures around the world. In this article Dr Sandra Garrido explains that in fact, our response to music is largely innate and is related to the evolutionary...Fifth Sense James Lind Alliance Priority Setting Partnership for smell and taste disorders
Research priorities in the past have been dominated by the quixotic curiosity of individual academics and the capricious generosity of funding organisations. There must be a better way... At Fifth Sense, research is fundamental to the work we do. Above...
Inner ear immunity
There is much speculation regarding the ear’s immune response. The environment in which we live and breathe is getting ever more complex; aspects such as the percentage of the population with autoimmune conditions are on the rise and, therefore, it...
A bittersweet finding
This is an elegant study, documenting the role of, and activation of, nitrous oxide in chronic sinusitis. Bitter taste receptors (TR2) have recently been identified as novel ‘players’ in sinonasal innate immunity and in chronic rhinosinusitis. The receptors are triggered...
The hippo and the nose
Chronic rhinosinusitis with nasal polyps (CRSwNP) leads to histological changes including thickening of the basilar membrane and epithelial proliferation. Molecular mechanisms underlying these changes are still not fully clear. A signalling pathway called the hippo with Yes‐associated protein (YAP) as...The changing spectrum of cancer of the oropharynx: dilemmas and future directions
The association of HPV in oropharyngeal cancer has identified a ‘new disease’, with its unique biologic behaviour, and challenges for clinicians in selecting therapeutic combinations offering maximum efficacy and minimum morbidity or long-term sequela currently under study in clinical trials....Ida Institute tackles clinician burn-out
Founded in 2007, Denmark’s Ida Institute is dedicated to the health of people with hearing loss. Its new four-part course, however, is aimed at another group: the medical professionals whose jobs can compromise their own health.Audiological and psychological consequences of single-sided deafness
The loss of sound input from one ear has a significant impact on our perception of our acoustic environment. This impact is compounded in adverse listening conditions. Rachel Knappett’s article explores the audiological impact of this hearing loss and the...
The polyp shrinker
Inflammatory markers, including T2 cells beta common (βc) cytokines IL-3, IL5 and granulocyte-macrophage colony-stimulating factor (GM-CSF), are known to play an important role in chronic rhinosinusitis with nasal polyps (CRSwNP). CSL311, a monoclonal antibody (mAb), was developed to target human...
