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Depth of invasion of oral cancer should be incorporated in new AJCC staging system
Since 1977, when the first edition of the Manual for Staging of Cancer was published by the American Joint Committee on Cancer (AJCC), the primary tumour staging for oral squamous cell carcinoma (SCC) has remained unchanged. In the last four...
eSRTs versus eCAP: Which is better?
Electrically evoked compound action potentials (eCAP) and electrically evoked stapedius reflex threshold (eSRT) techniques were compared to establish how well the two techniques correlated and which yielded quicker results in a group of paediatric cochlear implant (CI) users. This team...
Food impaction in children is associated with eosinophilic oesophagitis
There is an increasing amount of evidence to suggest that chronic oesophageal inflammation and motility disorders play a more significant role in oesophageal food impaction (EFI) in children compared to structural defects. The authors conducted a retrospective study of children...
Recurrent ENT infections in children – is it a sign of primary immunodeficiency disease?
ENT clinicians often come across children with recurrent ear, sinus and pulmonary infections. These recurrent infections, albeit common in childhood, can represent an early sign of primary immunodeficiency diseases (PIDD). PIDD is an underdiagnosed group of genetic disorders involving absent...
How to tackle the problem of ciprofloxacin-resistant ear infections?
The growing issue of ciprofloxacin-resistant ear organisms is certainly a pertinent one. The situation here in the UK, where ototoxic topical drops are frequently given initially in the presence of pus and a perforation, differs markedly from elsewhere where fluoroquinolones...
CRSwNP and smell – is it just the obstruction?
Anosmia and hyposmia are symptoms of CRS both with and without nasal polyps and can significantly affect quality of life. The nature of anosmia/hyposmia is thought to be both sensory-neural and conductive. These authors studied a mouse model in which...
Intratympanic steroids - to give or not to give?
The treatment of idiopathic sudden sensorineural hearing loss (ISSNHL) is controversial and different modes of steroids have been tried without any universal consensus. Various authors have reported combined oral and intratympanic steroid therapy in SSNHL, with consistent results in several...
Updates on current evidence for biologics in chronic rhinosinusitis
For a comparatively short piece, this article manages to pack in a lot of important information about a complex emerging area of rhinology – immunologically targeted therapy (biologics). Immunologically targeted therapy is a rapidly progressing and expanding domain which is...
To montelukast or not to montelukast
Both histamine and cysteinyl leukotrienes play an important role in both seasonal allergic rhinoconjunctivitis (SARC) and asthma. A combination therapy against both was shown to give benefit both in vitro and in vivo. Authors wanted to test the efficacy of...
Advances in neural stimulation of the auditory pathway
This article reviews the use of neuroprosthetic devices such as cochlear and auditory brainstem implants (ABI) to stimulate the auditory pathway, discussing the successes, limitations and advances in this area. Currently, neuroprosthetic devices deliver electrical impulses to the cochlear nerve...
The association between pregnancy and otosclerosis could be due to psychosocial factors around parenthood rather than biological factors
The association between pregnancy and otosclerosis is controversial. If pregnancy physiologically increases the likelihood of otosclerosis progression, then one would expect that there would be a difference between male and female patients with regards to whether having children affects how...
