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Genetic discovery using animal models: presbyacusis

By their very nature, late-onset hereditary disorders offer a large window of opportunity for therapeutic intervention. However, before we can begin to think about strategies we need knowledge of the genetics and pathology underlying the condition. In this article we...

The Graham Fraser Foundation

Graham Fraser (1936-94) was a pioneering otolaryngologist, in whose memory the Graham Fraser Foundation was set up, and an eponymous annual lecture and a travelling fellowship in otology were established. It’s an honour to profile the Foundation in this extended...

Experience on the front line

21st January 2021 Back to basics Yesterday I went right back to where my medical career began. I grew up in Germany, bilingual. A prerequisite to studying medicine in Germany is that applicants have to spend two months working as...

Cancer genetics and signalling pathways in ENT – a review and discussion of how this can be applied to rare tumours

Introduction Cancer cases continue to increase worldwide, and­­ head and neck cancer is a major global health issue, with an estimated global burden of over 630,000 new cases and over 350,000 deaths per year [1]. The term ‘head and neck...

Making audiology work during COVID-19 and beyond

‘New normal’ is another phrase that has become synonymous with this pandemic. In this article, consideration for ‘low-touch’ and ‘no touch’ audiological pathways are described for adoption as the ‘new normal’ for hearing healthcare. The COVID-19 crisis has ushered in...