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Precision and personalised genomic and epigenomic medicine in audiology/hearing loss
A detailed look at the pathogenesis of acquired hearing loss due to exposure to ototoxicity during pregnancy or shortly after birth. Insights from genomic medicine have shown that, along with environmental factors causing epigenetic alterations, hearing loss may be caused...
Neck dissection in adenoid cystic carcinoma is a risk worth taking?
This paper from Stanford University presents impressive figures to guide the debate on the extent of surgical management in adenoid cystic disease. Adenoid cystic carcinomas present a particular problem in that they can recur even after 20 years. They have...
What should be considered a ‘close’ margin in oral cavity squamous cell carcinoma?
Achieving clear margins during surgical resection in oral cavity squamous cell carcinoma (OCSCC) is thought to reduce local recurrence (LR) and improve prognosis; however, what constitutes a clear, close, or involved margin is inconsistent in the literature and in practice....
Follicle stimulating hormone receptors; an aid for the pathologist?
It is well known that Follicle Stimulating Hormone receptors (FSHRs) are found in extra-gonadal tumours such as those within thyroid tissue. This Polish study analysed 44 thyroid resection specimens to look for the presence of these receptors. No mention is...The Launch of the British Endoscopic Ear Group
The British Endoscopic Ear Group (BEEG) has been established to support the continued development and integration of endoscopic ear surgery (EES) within UK otological practice and training. Interest has grown steadily in recent years, driven by improved instrumentation, increasing published evidence, and a new generation of surgeons trained in both microscopic and endoscopic approaches.
Platelet-rich plasma-cartilage tympanoplasty
This systematic review and meta-analysis of five studies (n=234 patients) reports the effectiveness of type I tympanoplasty with cartilage and platelet-rich plasma (PRP) compared with type I cartilage tympanoplasty alone for closure of dry tympanic membrane perforations. This is an...Face to Face – facial reconstructive surgery mission in Ukraine
Face to Face is a humanitarian project to help those who have suffered facial trauma as a result of Russia's war against Ukraine.
