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In conversation with Jane Lea: the journey from athlete to surgeon
Dr Jane Lea is a clinical professor and fellowship director of otology and neurotology at the University of British Columbia. Prior to becoming a doctor, Jane was a semi-professional footballer and represented Canada. As a result of three knee operations,...In conversation with Jane Lea: the journey from athlete to surgeon
Dr Jane Lea is a clinical professor and fellowship director of otology and neurotology at the University of British Columbia. Prior to becoming a doctor, Jane was a semi-professional footballer and represented Canada. As a result of three knee operations,...
Gardasil vaccination as an adjuvant treatment for established recurrent laryngeal papillomatosis in male adults - does it stimulate an immune response?
Recurrent respiratory papillomatosis (RRP) is well known to be caused by infection with the human papilloma virus (types 6 and 11). Recurrence after surgical removal is common and potentially frequent and severe. Previous research has established that many patients with...
Tinnitus – Advances in Prevention, Assessment, and Management
This is a softcover volume, broken down into six sections over 406 pages printed in greyscale. The book is edited by AK Deshpande and JW Hall III, written by a large number of international experts in the field, and reviewed...
“Close” surgical margin in oral tongue redefined, 2.2mm is as good as 5mm
Gold standard treatment of squamous cell carcinoma (SCC) of the oral tongue remains surgical resection of the primary tumour with negative margins. The primary goal is the complete excision of the tumour with no residual cancer cells left behind. A...
Evidence for diagnostic role of narrow band imaging in the outpatient setting for head and neck squamous cell carcinoma
Narrow band imaging (NBI) uses light in the blue and green spectrum to differentiate areas of carcinoma from normal or inflammatory tissue. This tertiary referral head and neck unit in Spain used white light endoscopy as initial screening for all...
Sentinel nodes and UADT tumours
This is the review of a multicentre study to set practical guidelines for sentinel node techniques (SLN) in upper aerodigestive tract (UADT) squamous cell carcinomas including classical and extended indications. SLN biopsies are strictly indicated in patients with clinically and...
Expanding the role of FNA in thyroid nodule decision-making
Papillary thyroid cancer, the commonest histological type, has been extensively reported as having BRAF proto-oncogene mutations (most commonly the V600E mutation). There is great interest in BRAF as a molecular marker, particularly as a prognostic factor that may guide the...
Contemporary UK experience of oropharyngeal transoral laser microsurgery
It is well recognised that the current emergence of HPV-positive oropharyngeal squamous cell carcinoma (OPSCC) as a distinct disease entity requires a fresh look at standard treatment modalities that are based on chemoradiotherapy for stage III/IVa OPSCC. The Newcastle experience...
Difficult consultations with HPV-positive oropharnyeal cancer patients
The aetiological role of human papillomavirus (HPV) in oropharyngeal squamous cell carcinoma (OPSCC) is well established, and its incidence has massively increased over the last decade, whilst the incidence of HPV-negative OPSCC is declining. Although we know that HPV-positive OPSCC...
Postoperative radiation in early stage oropharyngeal squamous cell cancer (OPSCC)
There is significant variation in treatment strategies for OPSCC between units. This is largely due to unanswered questions which continue to exist beyond the published literature. We know that human papilloma virus status has a significant influence on prognosis but...
