You searched for "genes"

947 results found

Biologicals for severe chronic rhinosinusitis with nasal polyps. Any use?

Recent advances and knowledge of inflammatory endotypes of chronic rhinosinusitis with nasal polyps (CRSwNP) led to introduction of biological agents such as monoclonal antibodies targeting IgE (omalizumab) and Interleukins (ILs) such as IL4R alpha (dupilumab) and IL5. The European Academy...

Immunosuppresants and ototoxicity

There is a wide range of immunosuppressant drugs ranging from calcineurin inhibitors (e.g. cyclosporine), anti-folic agents (e.g. methotrexate) to anti-TNF and monoclonal antibodies, many of which could be ototoxic. The authors performed a systematic review assessing ototoxicity secondary to immunosuppressant...

Cochlear implants: recipient stories

The most powerful evidence for the remarkable achievements made with cochlear implants over 40 years comes from the life-changing, personal stories of those who have benefited from the technology. James Rylance I first noticed a problem with hearing when I...

Manuel Patricio Rodriguez Garcia (1805-1906): The ‘inventor of the laryngoscope’ and world-renowned singing teacher

Paris was the birthplace of the laryngoscope, invented by Manuel Garcia. As we are in Paris for IFOS 2017, Neil Weir tells us about this fascinating man, who travelled the world and was a renowned singer and laryngologist. Manuel Patricio...

Frederik Dikkers: championing change in laryngology

Prof Dikkers shares the details of his journey into ENT surgery, his dedication to treating laryngeal papillomatosis, and his pioneering advancements in button battery safety. Recurrent respiratory papillomatosis (RRP) is one of the most frustrating conditions managed by laryngologists. There...

In conversation with Gregory W. Randolph, President of the AAO-HNS

The American Academy of Otolaryngology – Head and Neck Surgery (AAO-HNS) is the world’s largest otolaryngology, head and neck surgical organisation. Declan Costello caught up with its new President, Dr Gregory W. Randolph. Dr Gregory W. Randolph. Congratulations on your...

Frederik Dikkers: championing change in laryngology

Prof Dikkers shares the details of his journey into ENT surgery, his dedication to treating laryngeal papillomatosis, and his pioneering advancements in button battery safety. Recurrent respiratory papillomatosis (RRP) is one of the most frustrating conditions managed by laryngologists. There...

Erasmus Darwin and the larynx – but why is it where it is and when?

Charles Darwin’s grandfather was not only on to where we all came from by the end of the 18th century, but dared to declare it in verse whilst resident in Lichfield Cathedral Close. This needed exceptional temerity, since not only...

OBITUARY: Dr David Pothier

David Pothier passed away on July 27, 2018 in the early hours of the morning following a struggle with recurrent brain cancer. His passing extinguished a brilliant light, the likes of which few of us will witness in our lifetime....

Teenagers with misophonia

Misophonia can be a distressing condition for teenagers and can have devastating effects upon their home and school lives. There is little research in this area and, as Lucy Partridge explains, more is greatly needed in order to identify interventions...

Anatomy for Plastic Surgery of the Face, Head, and Neck

This textbook couldn’t have arrived with better timing. As an ENT trainee soon to sit the FRCS(ORL-HNS) with an interest in facial plastics, I can comfortably say this is incredibly useful to have in the library. The book should suit...

Head, Neck, and Neuroanatomy (THIEME Atlas of Anatomy)

This is the second edition of Thieme’s popular head, neck and neuroanatomy atlas. There are 22 chapters on 530+ pages, with over 1300 full colour illustrations covering the full breadth of head, neck and neuroanatomy. It retails at £62.50 for...