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2421 results found

Risk factors for loco regional recurrence for oral SCC

Over 250,000 cases of oral squamous cell carcinomas are diagnosed annually worldwide with 128,000 registered deaths. The authors of this study are from a single institution in Germany and have conducted a retrospective audit of 517 patients with oral SCC...

Genetic discovery using animal models: presbyacusis

By their very nature, late-onset hereditary disorders offer a large window of opportunity for therapeutic intervention. However, before we can begin to think about strategies we need knowledge of the genetics and pathology underlying the condition. In this article we...

Staphylococcus aureus as a cause of refractory chronic rhinosinusitis

Staphylococcus aureus has long been linked to chronic rhinosinusitis, particularly recalcitrant cases. In this article, Alkis Psaltis describes how newer techniques have shown higher rates of S. aureus infection than were previously thought, and explains how the bacteria are able...

Remote hearing aid fittings and maintenance – exploring applications in Africa

Introduction Technology and connectivity are allowing audiological services to be provided in novel ways. The field of telehealth, although firmly established over the past two decades, is buoyed by the continued and rapid advances in information and communication technologies. Remote...

Sound localisation after bilateral cochlear implantation

Limited information is known about the localisation skills of paediatric cochlear implant patients who were good hearing aid users before their hearing deteriorated. As localisation is a skill often associated with good natural hearing, there is a worry that implants...

Exploring the role of oral microbiota in head and neck squamous cell carcinoma

Oral microbiota, especially Fusobacterium nucleatum, may improve survival and guide personalised treatment in head and neck squamous cell carcinoma. Head and neck squamous cell carcinoma (HNSCC) is a devastating disease with a low five-year survival rate that has shown little...

Transnasal oesophagoscopy (TNO)-guided secondary tracheoesophageal puncture (TEP) under local anaesthesia

Here, the authors describe a convenient use of the transnasal oesophagoscope to create a new tracheoesophageal puncture in the outpatient clinic setting. Tracheoesophageal puncture (TEP) with voice prosthesis insertion is a reliable and effective technique for surgical voice restoration (SVR)...

Mobile phones to assess productivity in rhinitis

Uncontrolled and moderate to severe allergic rhinitis (AR) has significant negative impact on work productivity. Work Productivity and Activity Impairment Allergic Specific Questionnaire (WPAI:AS) used to measure that impact showed this. Work productivity seems to improve when AR is treated....

ENT registrar national selection: how can we advise aspiring candidates?

With the aim of creating fair selection into the few available training numbers, ENT was one of the first surgical specialties to move to a national selection process for selecting new registrars in England. Since 2013 the selection process has...

Congenital cytomegalovirus causing deafness in children: an update

Congenital CMV is the leading non-genetic cause of sensorineural hearing loss in children. Keith Trimble draws our attention to this and gives a comprehensive guide on diagnosis and treatment. Congenital cytomegalovirus (cCMV) infection is common, affecting 1% of all newborns,...

Teenagers with misophonia

Misophonia can be a distressing condition for teenagers and can have devastating effects upon their home and school lives. There is little research in this area and, as Lucy Partridge explains, more is greatly needed in order to identify interventions...

Possibility of noise induced hearing loss during middle ear suction for secretory otitis media

Emission of high intensity sound is dangerous to the cochlea and can result in noise induced hearing loss (NIHL). Removal of middle ear fluid is common in everyday practice and the possibility of inducing NIHL is seldom considered and not...