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Underdiagnosing eosinophilic oesophagitis in food bolus obstruction: a wake-up call for ENT units

The management of FBO has evolved, with most cases now done by upper GI clinicians. Biopsies should be taken routinely to investigate possible eosinophilic oesophagitis. In acute soft food bolus obstruction (FBO), uncovering the root cause is as crucial as...

Pharma chameleon

One morning in September ’95, about a month into my first house job on the South Coast of England, I emerged from the ridiculously early ward round on the coronary care unit feeling a bit dazed and therefore headed off...

The structure and function of DNA

DNA structure and replication Genetic information within multicellular organisms, including man, is stored in molecules of deoxyribonucleic acid (DNA), which reside within the chromosomes of each cell nucleus. A DNA molecule consists of two very long chains, or strands, of...

What do animal models tell us about tinnitus and hyperacusis?

Do animals have tinnitus? The obvious question to ask is: do animals have tinnitus? It is known that tinnitus is a conscious percept and as such affected by attention and not audible during sleep. For it to be demonstrated that...

Innovation in medical product technologies

There is a point in all innovation projects where the clinician has exhausted their knowledge and needs expert help to create a prototype. Mark Prince, Design Engineer, discusses this phase of the project and how engineers’ analytical thinking brings a...

Cochlear implants for children

The field of cochlear implants in children has expanded remarkably over 40 years. Elizabeth Tyszkiewicz reflects on success and current challenges and calls for a national review of outcomes for young adults who received their implants in childhood. Aleena is...