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A useful adjuvant treatment for SNAC or IP
5-Fluorouracil (5FU) is a topical preparation used in the treatment of various dermatological, ocular and gynaecologic malignant and pre-malignant conditions, and this literature review looks at the efficacy of 5FU in treating inverted papilloma and sinonasal tumours. The authors cite...Erasmus Darwin and the larynx – but why is it where it is and when?
Charles Darwin’s grandfather was not only on to where we all came from by the end of the 18th century, but dared to declare it in verse whilst resident in Lichfield Cathedral Close. This needed exceptional temerity, since not only...
Measuring is understanding: an unsupervised PROM clustering of CRS patients
It has been clear for quite some years, at least for anyone dealing daily with chronic rhinosinusitis (CRS) patients, that CRS is an ‘umbrella’ diagnosis. There are significant differences between patients, including different demographic data, different endoscopic and radiographic images,...
Nasal polyps, does size matter?
This study from Germany investigates the correlation between nasal polyp size and return of olfactory function following endoscopic sinus surgery. Olfaction is affected more in patients with CRSwNP than with CRSsNP and the best chance of smell recovery occurs in...
Balloon dilatation of the eustachian tube - largely very safe but not entirely without risk
Consent is a fundamental part of our daily working lives. This is something as simple as consent to examine a patient, consent to undertake a procedure as minor as taking blood, through to consent for a major operation. Whatever the...The challenges of facemasks for people with hearing loss
Since the start of the COVID-19 pandemic we have seen an exponential increase in the use of face masks. Guidance around the globe varies on the use of face masks as an effective barrier to the coronavirus. Whereas in pre-covid...Worldwide picture of candidacy for cochlear implantation
Who should get a cochlear implant? Candidacy is one of the most important and widely discussed topics in the field of cochlear implantation. Here, Chris Raine and Debi Vickers outline cochlear implant candidacy in the UK, and compare this with...
Cochlear implantation in immunosuppressed patients. Is it feasible?
The effectiveness of cochlear implantation has led to a relaxation of the candidate criteria. Patients who had been rejected in the past may now be accepted and their outcomes are encouraging. However, the acceptance of immunosuppressed patients as cochlear implant...
Gadolinium enhanced MRI and the diagnosis of Ménière’s disease
Despite various criteria applied over the years to diagnose Ménière’s disease since the concept of endolymphatic hydrops was first observed in postmortem examinations of patients in 1938, the diagnosis still remains mainly clinical. To visualise endolymphatic hydrops in MRI imaging,...
