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Genetic discovery using animal models: presbyacusis

By their very nature, late-onset hereditary disorders offer a large window of opportunity for therapeutic intervention. However, before we can begin to think about strategies we need knowledge of the genetics and pathology underlying the condition. In this article we...

Hidden genetic disorders in children that may present to the otolaryngologist

Background Among the many hundreds of children presenting to the otolaryngology clinic are a few whose symptoms are due to an underlying genetic condition. In most cases the underlying syndrome is obvious and has already been diagnosed, such as the...

Advanced in-office awake rhinology

In-office awake rhinology transforms sinonasal care, offering safe, cost-effective, minimally invasive procedures with rapid recovery and high patient satisfaction. In recent years, the landscape of otolaryngological surgery has undergone a remarkable transformation with the advent of in-office awake surgical procedures....

What does functional neuroimaging tell us about tinnitus?

One of the most common causes of tinnitus is noise exposure, be that either cumulative day-to-day exposure over a lifetime or experience of acute noise trauma such as a loud concert or shooting incident. Observational data indicate that up to...

Adult hearing screening: consideration for a holistic model

Background Adult-onset hearing impairment is a highly prevalent and undertreated chronic problem that poses a significant burden of disease worldwide [1]. It is usually gradual and diagnosed and managed approximately 10 years after adults have first experienced hearing difficulties [2]....

Does diet have a role in the prevention of tinnitus?

Tinnitus, diet and healthy ageing Despite the high prevalence of tinnitus, its exact aetiology remains unclear. Research has explored the role of various biological pathways in the development of tinnitus including age-related changes in the auditory system, impaired vascular function,...

In conversation with Jane Lea: the journey from athlete to surgeon

Dr Jane Lea is a clinical professor and fellowship director of otology and neurotology at the University of British Columbia. Prior to becoming a doctor, Jane was a semi-professional footballer and represented Canada. As a result of three knee operations,...