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Genetics WG4. Improving diagnosis and drug development through the genetic understanding of tinnitus subtypes: a TINNET endeavour

Christopher R Cederroth and Jose Antonio Lopez-Escamez explain how progress is being made to investigate the contribution of genetic factors to tinnitus, including a subtype of ‘extreme’ tinnitus in Ménière’s disease. Genetics WG4 is working towards determining the genetic basis...

From Hippocrates to COVID-19: sniffing out the disease

The ancient Greek physician, Hippocrates, used the ‘art of smell’ to diagnose diseases around 400BC. He also formulated miasmatic theory, which posited that disease is caused by bad smells. Bad air was strongly believed by many physicians to be the...

Experience on the front line

21st January 2021 Back to basics Yesterday I went right back to where my medical career began. I grew up in Germany, bilingual. A prerequisite to studying medicine in Germany is that applicants have to spend two months working as...

The ups and downs of overseas research – the inner ear at altitude

Conducting research at extreme altitude presents unique challenges. This study of the inner ear at 5350m navigates setbacks in a quest for scientific discovery. Having completed a diploma in mountain medicine in my foundation years, I decided to undertake a...

Professor Heinz Stammberger’s pioneering contribution and legacy in the field of FESS

It is no exaggeration to say that functional endoscopic sinus surgery would not exist in its current form without Heinz Stammberger. Prof Valerie Lund traces the development of this relatively recent surgical technique. In the early 1980s, a happy combination...

Patient and public involvement in research

One step further from involving patients in setting research priorities is to involve them in the planning and recruitment stages of the subsequent trials and studies. Here, Carl Philpott and Aneeka Degun explain the concept of Patient and Public Involvement...

Smoking causes cancer – so what’s new?

You may well ask what is the novel value of a paper looking at smoking habits in patients with confirmed head and neck squamous cell carcinoma (HNSCC), but this paper highlights some pertinent points for clinical practice in the current...

Vestibular implantation: are we there yet?

The objectives of this review article were to ascertain, through a systematic literature review, device design, surgical approaches, objective and subjective outcomes as well as limitations of vestibular implantation (VI). Following an extensive systematic search using PRISMA guidelines, 21 studies...

Wisdom and the cochlear implant clinician

Helen Cullington provides the clinician’s perspective on the challenges faced in building artificial intelligence into cochlear implant clinics. She highlights the importance of including the clinician with their wisdom and experience to help make sense of the patterns of data....

The future of inner ear drug delivery

The techniques for delivering drugs to the inner ear system are evolving. Jeffrey Harris considers the myths, the facts and the potential for drug delivery innovations and how they can improve tomorrow’s hearing outcomes. The inner ear’s delicate membranous structure,...

Hearables: in-ear sensing devices for recording of physiological signals

Colver Ken Howe Ne, Jameel Muzaffar and Manohar Bance discuss the potential of hearable systems to monitor physiological signals (e.g. from brain or heart, blood pressure, body temperature) unobtrusively. Such adaptations require high-quality sensors and sophisticated de-noising signal processing on...

Balance and vestibular disorders in children

Discover the world of paediatric vestibular assessment and management from the team at Alder Hey Children’s Hospital, which is revolutionising services in this field. Dizziness and balance problems generate significant morbidity in children of all age groups. Vestibular disorders are...